Search Results
Overview
| Uniprot ID | A0A5G2RC74 |
|---|---|
| Protein Name | RuvB-like helicase |
| Gene Name | RUVBL2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 141 | IESLTKDKVQAGDVI |
| 189 | CPDGELQKRKEVVHT |
| 234 | VREQINAKVAEWREE |
| 320 | STSPYSEKDTKQILR |
| 323 | PYSEKDTKQILRIRC |
| 377 | SLVCRKRKGTEVQVD |
Function
Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding
Protein Sequence
10
MVGQLAARRA
20
AGVVLEMIRE
30
GKIAGRAVLI
40
AGQPGTGKTA
50
IAMGMAQALG
60
PDTPFTAIAG
70
SEIFSLEMSK
80
TEALTQAFRR
90
SIGVRIKEET
100
EIIEGEVVEI
110
QIDRPATGTG
120
SKVGKLTLKT
130
TEMETIYDLG
140
TKMIESLTKD
150
KVQAGDVITI
160
DKATGKISKL
170
GRSFTRARDY
180
DAMGSQTKFV
190
QCPDGELQKR
200
KEVVHTVSLH
210
EIDVINSRTQ
220
GFLALFSGDT
230
GEIKSEVREQ
240
INAKVAEWRE
250
EGKAEIIPGV
260
LFIDEVHMLD
270
IESFSFLNRA
280
LESDMAPVLI
290
MATNRGITRI
300
RGTSYQSPHG
310
IPIDLLDRLL
320
IVSTSPYSEK
330
DTKQILRIRC
340
GWGWCEEEDV
350
EMSEDAYTVL
360
TRIGLETSLR
370
YAIQLITAAS
380
LVCRKRKGTE
390
VQVDDIKRVY
400
SLFLDESRST
410
QYMKEYQDAF
420
LFNELKGETM
DTS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0120293 | dynein axonemal particle |
| Cellular Component | GO:0016363 | nuclear matrix |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0003678 | DNA helicase activity |
| Molecular Function | GO:0140296 | general transcription initiation factor binding |
| Biological Process | GO:0006310 | DNA recombination |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045739 | positive regulation of DNA repair |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.