Search Results

Overview

Uniprot IDA0A5G2RD08
Protein NameUDP-glucose ceramide glucosyltransferase-like 1
Gene NameUGGT1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1371 QIVRTDLKELRDFSL
1505 NPMTKEPKLEAAVRI
224 TSKSNAGKINYIFRH
364 TKARAITKTAVSSEL
967 PKGDTRIKYQFFEDR

Function

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation

Protein Sequence

10 WLGVGFHQIF 20 LGNTVQPVTH 30 LWVCHKMGLL 40 IILIGLWLLS 50 SVKADSKAIT 60 TSLTTKWFST 70 PLLLEASEFL 80 AEDSQEKFWN 90 FVEASQNIGS 100 SDHHGTDYAY 110 YHAILEAAFQ 120 FLSPLQQNLL 130 KFCLSLRSYS 140 ATIQAFQQIA 150 ADEPPPEGCN 160 SFFSVHGKRS 170 CDFDTLETLL 180 LTASERPKPL 190 LFKGDHRYPS 200 SNPESSVVIF 210 YSEIGSEEFY 220 NFHRQLTSKS 230 NAGKINYIFR 240 HYIPNPRKEP 250 VYLSGYGVEL 260 AIKSTEYKAK 270 DDTQVKGTEV 280 NTTVIGENDP 290 IDEVQGFLFG 300 KLRDLHPDLK 310 GQLKELRKHL 320 VESTNEMAPL 330 KVWQLQDLSF 340 QTAARILAAP 350 IELALVIMKD 360 LSQNFPTKAR 370 AITKTAVSSE 380 LRTEVEENQK 390 YFKGALGLQP 400 GDSALFINGL 410 HIDLETQDIF 420 SLFDILRNEA 430 RVMEGLHRLG 440 IEGLSLHNIL 450 KLNIQPSEAD 460 YAVDIRSPAI 470 SWINNLELDS 480 RYSSWPSSLQ 490 ELLRPTFPGV 500 IRQIRKNLHN 510 MVFIVDPAHE 520 STAELINTAE 530 MFLSNHIPLR 540 LGLIFVVNDS 550 EDVDGMQDAG 560 VALLRAYNYV 570 AQEMDDYHAF 580 QTLTHIYNKV 590 RTGEKVKVEH 600 VVSVLEKKYP 610 YVEVNSILGI 620 DSAYDQNRKE 630 ARGYYEQTGV 640 GPLPVVLFNG 650 MPLEKEQLDP 660 DELETITMHK 670 ILETTTFFQR 680 AVYLGELSLD 690 QDVVEYIMNQ 700 PNVVPRINSR 710 ILTAEREYLD 720 LTATNNFFVD 730 DYARFTVLDS 740 QGKTTAIANS 750 MNYLTKKGMS 760 SKEIYDDSFI 770 RPVTFWIVGD 780 FDSPSGRQLL 790 YDAIKHQKSS 800 NNVRIGMINN 810 PSEDISYEKT 820 QISRAIWAAL 830 QTQTSNSAKN 840 FITKMAKEET 850 AEALAAGADI 860 SEFSVGGMDF 870 SLFKEVFESS 880 KMDFILSHAM 890 YCRDVLKLKK 900 GQRAVISNGR 910 IIGPLEDSEL 920 FNQDDFHLLE 930 NIILKTSGQK 940 IKSHIQQLRV 950 EEDVASDLVM 960 KVDALLSAQP 970 KGDTRIKYQF 980 FEDRHSAIKL 990 KPKEGETYFD 1000 VVAVVDPVTR 1010 EAQRLAPLLL 1020 VLTQLINMNL 1030 RVFMNCQSKL 1040 SDMPLKSFYR 1050 YVLEPEISFS 1060 SDNSFAKGPI 1070 AKFLDMPQSP 1080 LFTLNLNTPE 1090 SWMVESVRTP 1100 YDLDNIYLEE 1110 VDSIVAAEYE 1120 LEYLLLEGHC 1130 YDITTGQPPR 1140 GLQFTLGTSA 1150 KPVIVDTIVM 1160 ANLGYFQLKA 1170 NPGAWILRLR 1180 KGRSEDIYRI 1190 YSHDGTDSPP 1200 DADEVVVVLN 1210 NFKSKIIKVK 1220 VQKKADMVNE 1230 DLLSDGTNEN 1240 ESGFWDSFKW 1250 GFTGGQKTEE 1260 VKQDKDDVIN 1270 IFSVASGHLY 1280 ERFLRIMMLS 1290 VLKNTKTPVK 1300 FWFLKNYLSP 1310 TFKEFIPYMA 1320 NKYNFQYELV 1330 QYKWPRWLHQ 1340 QTEKQRIIWG 1350 YKILFLDVLF 1360 PLVVDKFLFV 1370 DADQIVRTDL 1380 KELRDFSLDG 1390 APYGYTPFCD 1400 SRREMDGYRF 1410 WKSGYWASHL 1420 AGRKYHISAL 1430 YVVDLKKFRK 1440 IAAGDRLRGQ 1450 YQGLSQDPNS 1460 LSNLDQDLPN 1470 NMIHQVPIKS 1480 LPQEWLWCET 1490 WCDDASKKRA 1500 KTIDLCNNPM 1510 TKEPKLEAAV 1520 RIVPEWQDYD 1530 QEIKQLQTRF 1540 QEEKEMGTLY 1550 KDMTAEEPSR 1560 EGMYRLKKEI EKAVI

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005788 endoplasmic reticulum lumen
Cellular Component GO:0032991 protein-containing complex
Molecular Function GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Molecular Function GO:0051082 unfolded protein binding
Biological Process GO:0009101 glycoprotein biosynthetic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.