Search Results
Overview
| Uniprot ID | A0A5G2RD78 |
|---|---|
| Protein Name | NEDD8-activating enzyme E1 catalytic subunit |
| Gene Name | UBA3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 353 | RLTQGVVKRIIPAVA |
Function
Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8
Protein Sequence
10
MADGEEPEKK
20
RRRIEELLAE
30
KMAVDGGCGD
40
TGDWEGRWNH
50
VKKFLERSGP
60
FTHPDFEPST
70
ESLQFLLETC
80
KVLVIGAGGL
90
GCELLKNLAL
100
SGFRQIHVID
110
MDTIDVSNLN
120
RQFLFRPKDV
130
GRPKAEVAAE
140
FLNDRVPNCN
150
VVPHFNKIQD
160
FNDTFYRQFH
170
IIVCGLDSII
180
ARRWINGMLI
190
SLLNYEDGVL
200
DPSSIVPLID
210
GGTEGFKGNA
220
RVILPGMTAC
230
IECTLELYPP
240
QVNFPMCTIA
250
SMPRLPEHCI
260
EYVRILQWPK
270
EQPFGGNKPN
280
FTIQIYVRYL
290
SMLFIWKITL
300
KISWSLFTCF
310
CLPFLFFLPL
320
TEGVPLDGDD
330
PDHIQWIFQK
340
SLERASQYNI
350
RGVTYRLTQG
360
VVKRIIPAVA
370
STNAVIAAVC
380
ATEVFKIATS
390
AYIPLNNYLV
400
FNDVDGLYTY
410
TFEAERKENC
420
PACSQLPQNI
430
QFSPSAKLQE
440
VLDYLTNSAS
450
LQMKSPAITA
460
TLEGKNRTLY
470
LQSVTSIEER
480
TRPNLSKTLK
490
ELGLVDGQEL
500
AVADVTTPQT
VLFKLHFTS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0019781 | NEDD8 activating enzyme activity |
| Biological Process | GO:0045116 | protein neddylation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.