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Overview

Uniprot IDA0A5G2RD82
Protein NameElongation factor 1-beta
Gene NameEEF1B2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
102 LRWYNHIKSYEKEKA
108 IKSYEKEKASLPGVK
115 KASLPGVKKALGKYG
171 RLAQYESKKAKKPAL
227 VPVGYGIKKLQIQCV

Function

Catalytic subunit of the guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) of the eukaryotic elongation factor 1 complex (eEF1). Stimulates the exchange of GDP for GTP on elongation factor 1A (eEF1A), probably by displacing GDP from the nucleotide binding pocket in eEF1A

Protein Sequence

10 MSRLDQRKES 20 HQGTNSEGQA 30 LGSLACAPFF 40 LRCGPVPRST 50 IAMGFGDLKS 60 PAGLQVLNDY 70 LADKSYIEGY 80 VPSQADVAVF 90 EAVSGPPPAD 100 LCHALRWYNH 110 IKSYEKEKAS 120 LPGVKKALGK 130 YGPANVEDTT 140 ESGATDSKDD 150 DDIDLFGSDD 160 EEESEEAKRL 170 REERLAQYES 180 KKAKKPALVA 190 KSSILLDVKP 200 WDDETDMAKL 210 EECVRSIQAD 220 GLVWGSSKLV 230 PVGYGIKKLQ 240 IQCVVEDDKV 250 GTDMLEEQIT 260 AFEDYVQSMD VAAFNKI

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005853 eukaryotic translation elongation factor 1 complex
Molecular Function GO:0003746 translation elongation factor activity

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.