Search Results
Overview
| Uniprot ID | A0A5G2RD86 |
|---|---|
| Protein Name | Signal recognition particle subunit SRP68 |
| Gene Name | SRP68 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 209 | AAIEAFNKCKTIYEK |
| 302 | RGRAVPVKVDRVRIF |
| 389 | IKLSTAIKRNENMAR |
| 448 | EEDRAFQKEIGLKTL |
| 453 | FQKEIGLKTLVYKAY |
| 474 | QSYVLVKKWSEALVL |
| 607 | DKLEQKTKSGLAGYI |
Function
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER
Protein Sequence
10
MAAEKQVPGG
20
GGGSSGGGGG
30
GSSGGGRGAG
40
GEENKENERP
50
SAGSKANKEF
60
GDSLSLEILQ
70
IIKESQQQHG
80
LRHGDFQRYR
90
GYCSRRQRRL
100
RKTLNFKMGN
110
RHKFTGKKVT
120
EDLLTDNRYL
130
LLVLMDAERA
140
WSYAMQLKQE
150
ANTEPRKRFH
160
LLSRLRKAVK
170
HAEELERLCE
180
SNRVDAKTKL
190
EAQAYTAYLS
200
GMLRFEHQEW
210
KAAIEAFNKC
220
KTIYEKLASA
230
FTEEQAVLYN
240
QRVEEISPNI
250
RYCAYNIGDQ
260
SAINELMQMR
270
LRSGGTEGLL
280
AEKLEALITQ
290
TRAKQAATMS
300
EVEWRGRAVP
310
VKVDRVRIFL
320
LGLADNEAAI
330
AQAESEETKE
340
RLFESMLSEC
350
RDAIQAVREE
360
LKPDQKQRDY
370
PLDGESGKVS
380
NLQYLHSYLT
390
YIKLSTAIKR
400
NENMARGLQK
410
ALLQQQPEDD
420
GKRSPRPQDL
430
IRLYDIILQN
440
LVELLQLPGL
450
EEDRAFQKEI
460
GLKTLVYKAY
470
RCFFIAQSYV
480
LVKKWSEALV
490
LYDRVLKYAD
500
EVNSDAGAFK
510
NSLKDLPDVL
520
ELISQVRSEK
530
CCLQAAAILD
540
TNDPQQTETS
550
SQVKDNKPLV
560
ERFETFCLDP
570
SLVTKQANLV
580
HFPPGFQPVP
590
CKPLFFDLAL
600
NHVAFPPLED
610
KLEQKTKSGL
620
AGYIKGIFGF
RS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting |
| Molecular Function | GO:0008312 | 7S RNA binding |
| Molecular Function | GO:0030942 | endoplasmic reticulum signal peptide binding |
| Molecular Function | GO:0005047 | signal recognition particle binding |
| Biological Process | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.