Search Results
Overview
| Uniprot ID | A0A5G2RDA8 |
|---|---|
| Protein Name | Septin |
| Gene Name | SEPTIN7 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 165 | FMKRLHEKVNIIPLI |
| 187 | PEECQQFKKQIMKEI |
| 192 | QFKKQIMKEIQEHKI |
| 198 | MKEIQEHKIKIYEFP |
| 352 | KEKVQKLKDSEAELQ |
| 68 | GPSHRIKKTVQVEQS |
| 76 | TVQVEQSKVLIKEGG |
Function
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation
Protein Sequence
10
QQQKNLEGYV
20
GFANLPNQVY
30
RKSVKRGFEF
40
TLMVVGESGL
50
GKSTLINSLF
60
LTDLYSPEYP
70
GPSHRIKKTV
80
QVEQSKVLIK
90
EGGVQLLLTI
100
VDTPGFGDAV
110
DNSNCWQPVI
120
DYIDSKFEDY
130
LNAESRVNRR
140
QMPDNRVQCC
150
LYFIAPSGHG
160
LKPLDIEFMK
170
RLHEKVNIIP
180
LIAKADTLTP
190
EECQQFKKQI
200
MKEIQEHKIK
210
IYEFPETDDE
220
EENKLVKKIK
230
DRLPLAVVGS
240
NTIIEVNGKR
250
VRGRQYPWGV
260
AEVENGEHCD
270
FTILRNMLIR
280
THMQDLKDVT
290
NNVHYENYRS
300
RKLAAVTYNG
310
VDNNKNKGQL
320
TKSPLAQMEE
330
ERREHVAKMK
340
KMEMEMEQVF
350
EMKVKEKVQK
360
LKDSEAELQR
370
RHEQMKKNLE
380
AQHKELEEKR
390
RQFEDEKANW
400
EAQQRILEQQ
410
NSSRTLEKNK
KKGKIF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0032154 | cleavage furrow |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0031105 | septin complex |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0005525 | GTP binding |
| Biological Process | GO:0051301 | cell division |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.