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Overview

Uniprot IDA0A5G2REF7
Protein NameMitochondrial pyruvate carrier
Gene NameMPC1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
72 TFMRFAYKVQPRNWL

Function

Mediates the uptake of pyruvate into mitochondria

Protein Sequence

10 MAGALVRKAA 20 DYVRSKDFRD 30 YLMSTHFWGP 40 VANWGLPIAA 50 INDMKKSPEI 60 ISGRMTFALC 70 CYSLTFMRFA 80 YKVQPRNWLL 90 FACHATNEVA 100 QLIQGGRLIR HEMSKKASA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Molecular Function GO:0050833 pyruvate transmembrane transporter activity
Biological Process GO:0006850 pyruvate import into mitochondria

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.