Search Results
Overview
| Uniprot ID | A0A5G2RF09 |
|---|---|
| Protein Name | U6 snRNA-associated Sm-like protein LSm7 |
| Gene Name | LSM7 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 68 | DLSKYIDKTIRVKFQ |
| 73 | IDKTIRVKFQGGREA |
Function
Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA
Protein Sequence
10
MCRGQRPKGA
20
ARRRRQDGGE
30
RAARLAWLEG
40
LAGQNLAALP
50
PSRNVLSSQD
60
KEKKKKESIL
70
DLSKYIDKTI
80
RVKFQGGREA
90
SGILKGFDPL
100
LNLVLDGTIE
110
YMRDPDDQYK
120
LTEDTRQLGL
130
VVCRGTSVVL
140
ICPQDGMEAI
150
PNPFIQQQDA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0120115 | Lsm2-8 complex |
| Cellular Component | GO:0071005 | U2-type precatalytic spliceosome |
| Cellular Component | GO:0046540 | U4/U6 x U5 tri-snRNP complex |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0000956 | nuclear-transcribed mRNA catabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.