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Overview

Uniprot IDA0A5G2RGH7
Protein NameStress-activated protein kinase JNK
Gene NameMAPK10
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
139 KPSNIVVKSDCTLKI
230 PCPEFMKKLQPTVRN

Function

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity

Protein Sequence

10 RQETVELDPF 20 PVDEKPYKQC 30 AAYDAVLDRN 40 VAIKKLSRPF 50 QNQTHAKRAY 60 RELVLMKCVN 70 HKNIISLLNV 80 FTPQKTLEEF 90 QDVYLVMELM 100 DANLCQVIQM 110 ELDHERMSYL 120 LYQMLCGIKH 130 LHSAGIIHRD 140 LKPSNIVVKS 150 DCTLKILDFG 160 LARTAGTSFM 170 MTPYVVTRYY 180 RAPEVILGMG 190 YKENVDIWSV 200 GCIMGEMVRH 210 KILFPGRDYI 220 DQWNKVIEQL 230 GTPCPEFMKK 240 LQPTVRNYVE 250 NRPKYAGLTF 260 PKLFPDSLFP 270 ADSEHNKLKA 280 SQARDLLSKM 290 LVIDPAKRIS 300 VDDALQHPYI 310 NVWYDPAEVE 320 APPPQIYDKQ 330 LDEREHTIEE 340 WKELIYKEVM 350 LSEEKTKNGV 360 VKGQPSPSAQ VQQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0004707 MAP kinase activity
Molecular Function GO:0106310 protein serine kinase activity
Biological Process GO:0048511 rhythmic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.