Search Results
Overview
| Uniprot ID | A0A5G2RHB2 |
|---|---|
| Protein Name | Gephyrin |
| Gene Name | GPHN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 109 | PVCGIRGKTLIINLP |
| 295 | TASCPTPKVQSRCSS |
Function
Also has a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released
Protein Sequence
10
MATEGMILTN
20
HDHQIRVGVL
30
TVSDSCFRNL
40
AEDRSGINLK
50
DLVQDPSFIY
60
SVYYKVWFID
70
SIIYKYFKLI
80
LLLLIEREAP
90
GMALAMLMGS
100
LNVTPLGMLS
110
RPVCGIRGKT
120
LIINLPGSKK
130
GSQECFQFIL
140
PALPHAIDLL
150
RDAIVKVKEV
160
HDELEDLPSP
170
PPPLSPPPTT
180
SPHKQTEDKG
190
VQCEEEEEEK
200
KDSGVASTED
210
SSSSHITAAA
220
IAAKKHPFYT
230
SPAVIMAHGE
240
QPIPGLISYS
250
HDATGSAEEP
260
IPDSIISRGV
270
QVLPRDTASL
280
STTPSESPRA
290
QATSRLSTAS
300
CPTPKVQSRC
310
SSKENILRAS
320
HSAVDITKVA
330
RRHRMSPFPL
340
TSMDKAFITV
350
LEMTPVLGTE
360
IINYRDGMGR
370
VLAQDVYAKD
380
NLPPFPASVK
390
DGYAVRAADG
400
PGDRFIIGES
410
QAGEQPTQTV
420
MPGQVMRVTT
430
GAPIPCGADA
440
VVQVEDTELI
450
RESDDGTEEL
460
EVRILVQARP
470
GQDIRPIGHD
480
IKRGECVLAK
490
GTHMGPSEIG
500
LLATVGVTEV
510
EVNKFPVVAV
520
MSTGNELLNP
530
EDDLLPGKIR
540
DSNRSTLLAT
550
IQEHGYPTIN
560
LGIVGDNPDD
570
LLNALNEGIS
580
RADVIITSGG
590
VSMGEKDYLK
600
QVLDIDLHAQ
610
IHFGRVFMKP
620
GLPTTFATLD
630
IDGVRKIIFA
640
LPGNPVSAVV
650
TCNLFVVPAL
660
RKMQGILDPR
670
PTIIKARLSC
680
DVKLDPRPEY
690
HRCILTWHHQ
700
EPLPWAQSTG
710
NQMSSRLMSM
720
RSANGLLMLP
730
PKTEQYVELH
740
KGEVVDVMVI
GRL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005856 | cytoskeleton |
| Molecular Function | GO:0061599 | molybdopterin molybdotransferase activity |
| Biological Process | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process |
| Biological Process | GO:0072657 | protein localization to membrane |
| Biological Process | GO:0050808 | synapse organization |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0045211 | postsynaptic membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0061598 | molybdopterin adenylyltransferase activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.