Search Results
Overview
| Uniprot ID | A0A5G2RHV3 |
|---|---|
| Protein Name | Notchless protein homolog 1 |
| Gene Name | NLE1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 226 | RYVASSSKDGSVRVW |
Function
Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival
Protein Sequence
10
RLRRWFPQDE
20
AAPRDVQRLL
30
VQFQDEGGQL
40
LGSPFDVPVD
50
ITPDKLQLVC
60
NALLAQEDPL
70
PLAFYVHDAE
80
IISSLGKTLE
90
SQAVETEKVL
100
DIIYQPQAVF
110
RVRAVTRCTS
120
SLEGHSEAVI
130
SVAFSPTGKY
140
LASGSGDTTV
150
RFWDLSTETP
160
HFTCQGHRHW
170
VLSISWSPDG
180
KKLASGCKNG
190
QILLWDPSTG
200
KQVGRALAGH
210
SKWITALSWE
220
PLHANPECRY
230
VASSSKDGSV
240
RVWDTTAGRC
250
ERILTGHTQS
260
VTCLRWGGDG
270
LLYSASQDRT
280
IKVWRAHDGV
290
LCRTLQGHGH
300
WVNTMALSTD
310
YALRTGAFEP
320
AEASVNAQDL
330
RGSLQELKER
340
ALSRYNLVRG
350
RGLERLVSGS
360
DDFTLFLWSP
370
AEDKKPLARM
380
TGHQALINQV
390
LFSPDSRIIA
400
SASFDKSIKL
410
WDGRTGKYLA
420
SLRGHVAAVY
430
QIAWSADSRL
440
LVSGSSDSTL
450
KVWDVKAQKL
460
AADLPGHADE
470
VYAVDWSPDG
480
QRVASGGKDK
CLRM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005730 | nucleolus |
| Biological Process | GO:0007219 | Notch signaling pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.