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Overview

Uniprot IDA0A5G2RHW3
Protein NameDual specificity mitogen-activated protein kinase kinase 2
Gene NameMAP2K2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
108 KLIHLEIKPAIRNQI

Function

No function data available.

Protein Sequence

10 MLARRKPVLP 20 ALTINPAIAE 30 GPSPTSEGAS 40 EANLVDLQKK 50 LEELELDEQQ 60 KKRLEAFLTQ 70 KAKVGELKDD 80 DFERISELGA 90 GNGGVVTKVQ 100 HRPSGLIMAR 110 KLIHLEIKPA 120 IRNQIIRELQ 130 VLHECNSPYI 140 VGFYGAFYSD 150 GEISICMEHM 160 DGGSLDQVLK 170 EAKRIPEEIL 180 GKVSIAVLRG 190 LAYLREKHQI 200 MHRDVKPSNI 210 LVNSRGEIKL 220 CDFGVSGQLI 230 DSMANSFVGT 240 RSYMSPERLQ 250 GTHYSVQSDI 260 WSMGLSLVEL 270 SIGRYPIPPP 280 DAKELEAIFG 290 RPMVDGGDGE 300 PHSISPRPRP 310 PGRPISAAQS 320 RPPPKLPNGV 330 FTQDFQEFVN 340 KCLIKNPAER 350 ADLKMLMNHT 360 FIKRSEVEEV 370 DFAGWLCKTL 380 RLNQPSTPTR TAV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005769 early endosome
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0005770 late endosome
Cellular Component GO:0005739 mitochondrion
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0004708 MAP kinase kinase activity
Molecular Function GO:0004674 protein serine/threonine kinase activity
Molecular Function GO:0004713 protein tyrosine kinase activity
Biological Process GO:2000641 regulation of early endosome to late endosome transport
Biological Process GO:0090170 regulation of Golgi inheritance
Biological Process GO:0032872 regulation of stress-activated MAPK cascade

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.