Search Results
Overview
| Uniprot ID | A0A5G2RI25 |
|---|---|
| Protein Name | Calponin |
| Gene Name | CNN3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | IGVKYAEKQTRRFDE |
| 109 | TRRFDEGKLKAGQSV |
| 111 | RFDEGKLKAGQSVIG |
| 17 | YGLSAEVKNKIASKY |
| 209 | TNKVASQKGMSVYGL |
| 23 | VKNKIASKYDHQAEE |
| 6 | **MTHFNKGPSYGLS |
| 70 | KLQPGSVKKVNESSL |
Function
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity
Protein Sequence
10
MTHFNKGPSY
20
GLSAEVKNKI
30
ASKYDHQAEE
40
DLRNWIEVTG
50
MSIGTSFQLG
60
LKDGIILCEL
70
INKLQPGSVK
80
KVNESSLNWP
90
QAKTKGFHTT
100
IDIGVKYAEK
110
QTRRFDEGKL
120
KAGQSVIGLQ
130
MGTNKCASQA
140
GMTAYGTRRH
150
LYDPKMQTDK
160
PFDQTTISLQ
170
MGTNKGASQA
180
GMLAPGTRRD
190
IYDQKLTLQP
200
VDNSTISLQM
210
GTNKVASQKG
220
MSVYGLGRQV
230
YDPKYCAAPT
240
EPVIHNGSQG
250
TGTNGSEISD
260
SDYQAEYPDE
270
YHGEYPDDYP
280
RDYQYGDQGI
DY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Biological Process | GO:0031032 | actomyosin structure organization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.