Search Results
Overview
| Uniprot ID | A0A5G2RLU2 |
|---|---|
| Protein Name | Cleavage and polyadenylation specificity factor subunit 4 |
| Gene Name | CPSF4 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 69 | GEKTVVCKHWLRGLC |
Function
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U)
Protein Sequence
10
MQEIIASVDH
20
IKFDLEIAVE
30
QQLGAQPLPF
40
PGMDKSGAAV
50
CEFFLKAACG
60
KGGMCPFRHI
70
SGEKTVVCKH
80
WLRGLCKKGD
90
QCEFLHEYDM
100
TKMPECYFYS
110
KFGECSNKEC
120
PFLHIDPESK
130
IKDCPWYDRG
140
FCKHGPLCRH
150
RHTRRVICVN
160
YLVGFCPEGP
170
SCKFMHPRFE
180
LPMGTTEQPP
190
LPQQTQPPAK
200
VPCPRPVVLP
210
ALAVPLQQKT
220
QCPPQCGAAL
230
DLAGDRVRGR
240
GPPRPSRKSR
250
QQSSWHPPLG
260
VEGRLPEPGP
270
TCVSLPACQR
280
PGVECRAAWG
290
LRFQPFPLPV
GLT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0031124 | mRNA 3'-end processing |
| Cellular Component | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:1990837 | sequence-specific double-stranded DNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.