Search Results
Overview
| Uniprot ID | A0A5K1V5T2 |
|---|---|
| Protein Name | Junctional adhesion molecule A |
| Gene Name | F11R |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 39 | EVRVAENKPAKLSCS |
| 42 | VAENKPAKLSCSYSG |
Function
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation
Protein Sequence
10
FGSSCKIGVV
20
ILVLLICSLT
30
LGRGAVYTSE
40
PEVRVAENKP
50
AKLSCSYSGF
60
SSPRVEWKFT
70
HGDITSLVCY
80
NNKITASYEN
90
RVTFSASGIT
100
FHSVTRKDTG
110
TYTCMVSDEG
120
GNTYGEVTVN
130
LIVLVPPSKP
140
TISVPSSATI
150
GNRAVLTCSE
160
KDGSPPSEYF
170
WFKDGVLMPT
180
EPKSNRAFIN
190
SSYSLNPKTG
200
ELIFDPVSAS
210
DAGDYTCEAQ
220
NGYGSPMRSD
230
TVHMEAAELN
240
VGGIVAAVLV
250
TLILLGVLIF
260
GIWFAYSRGY
270
FDSKYLTSSK
280
KVIYSQPTAR
290
RGIQTDLIIL
300
GVTLVHASPV
310
SSVLALLRCY
320
QTLAPDVCSF
330
TGCLICVLAP
340
TRPPTFILEC
CF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005923 | bicellular tight junction |
| Cellular Component | GO:0005886 | plasma membrane |
| Biological Process | GO:0007155 | cell adhesion |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0003008 | system process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.