Search Results

Overview

Uniprot IDA0A5K1V6L8
Protein NameIntegrin alpha-V
Gene NameITGAV
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
133 SVRSKQDKILACAPL
498 PLPGTDLKVSCFHVR
509 FHVRFCLKADGKGTL

Function

No function data available.

Protein Sequence

10 MASLPRRRLR 20 LRPRRLLLLL 30 PGFLLPLCGA 40 FNLDVDSPAE 50 YSGPEGSYFG 60 FAVDFFVPSA 70 SSMFLLVGAP 80 KANTTQPGIV 90 EGGQVLKCDW 100 SSHRGCQPIE 110 FDATGNRDYA 120 KDDPLEFKSH 130 QWFGASVRSK 140 QDKILACAPL 150 YHWRTEMKQE 160 REPVGTCFLQ 170 DGTKTVEYAP 180 CRSKNIDADG 190 QGFCQGGFSI 200 DFTKADRVLL 210 GGPGSFYWQG 220 QLISDQVAEI 230 VSKYDPKVYS 240 IKYNNQLATR 250 TAQAIFDDSY 260 LGYSVAVGDF 270 NGDGIDDFVS 280 GVPRAARTLG 290 MVYIYDGKNM 300 SSLHNFTGEQ 310 MAAYFGFSVA 320 ATDINGDDYA 330 DVFIGAPLFM 340 DRGSDGKLQE 350 VGQVSVSLQK 360 ASGNFQTTKL 370 NGFEVFARFG 380 SAIAPLGDLD 390 QDGFNDIAIA 400 APYGGEDKKG 410 IVYIFNGRPT 420 GLNAVPSQIL 430 EGKWAARSMP 440 PSFGYSMKGA 450 TDIDKNGYPD 460 LIVGAFGVDR 470 AVLYRARPVI 480 TVNAGLEVYP 490 SILNQDNKTC 500 PLPGTDLKVS 510 CFHVRFCLKA 520 DGKGTLPTKL 530 NFQVELLLDK 540 LKQKGAIRRA 550 LFLHNRFPGH 560 SKNMTISRGG 570 QMQCEELIAY 580 LRDESEFRDK 590 LTPITIFMEY 600 RLDYTTAADV 610 TGLQPILNQF 620 TPANISRQAH 630 ILLDCGEDNV 640 CKPKLEVSVD 650 RFVFTCSDQK 660 KIYVGDDNPL 670 TLIVKAQNQG 680 EGAYEAELIV 690 SIPPQADFIG 700 VVRNSEALAR 710 LSCAFKTENQ 720 TRQVVCDLGN 730 PMKAGTQLLA 740 GLRFSVQQQS 750 EMDTSVKFDL 760 QIQSSNLFDK 770 VSPVVSYKVD 780 LAVLAAVEIR 790 GVSSPDHIFL 800 PIPNWEHKEN 810 PETEEDVGPV 820 VQHIYELRNN 830 GPSSFSKAML 840 NLQWPYKYNN 850 NTLLYILQYD 860 IDGPMNCTSD 870 MEINPLRIKI 880 SNSQTEKNDT 890 VGGQGDRNHL 900 VTKRDLTLIE 910 GDVHTLGCGI 920 AECLKIVCQV 930 GRLDRGKSAI 940 LYVKSLLWTE 950 TFMNKENQNH 960 SYSLKSSASF 970 NVIEFPYKNL 980 PIEDIFNSTL 990 VTTNVTWGIQ 1000 PAPMPVPVWV 1010 IILAVLAGLL 1020 LLAVLVFVMY 1030 RMGFFKRVRP 1040 PQEEQEREQL 1050 QPHENGEGNS ET

Gene Ontology

Classification GO ID Description
Cellular Component GO:0035868 alphav-beta3 integrin-HMGB1 complex
Cellular Component GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex
Cellular Component GO:0009986 cell surface
Cellular Component GO:0009897 external side of plasma membrane
Cellular Component GO:0031527 filopodium membrane
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0034682 integrin alphav-beta1 complex
Cellular Component GO:0034683 integrin alphav-beta3 complex
Cellular Component GO:0034684 integrin alphav-beta5 complex
Cellular Component GO:0034685 integrin alphav-beta6 complex
Cellular Component GO:0034686 integrin alphav-beta8 complex
Cellular Component GO:0031258 lamellipodium membrane
Cellular Component GO:0031528 microvillus membrane
Cellular Component GO:0032587 ruffle membrane
Molecular Function GO:0019960 C-X3-C chemokine binding
Molecular Function GO:0015026 coreceptor activity
Molecular Function GO:0050840 extracellular matrix binding
Molecular Function GO:1990430 extracellular matrix protein binding
Molecular Function GO:0017134 fibroblast growth factor binding
Molecular Function GO:0001968 fibronectin binding
Molecular Function GO:0031994 insulin-like growth factor I binding
Molecular Function GO:0005178 integrin binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0038132 neuregulin binding
Molecular Function GO:0001846 opsonin binding
Molecular Function GO:0002020 protease binding
Molecular Function GO:0005080 protein kinase C binding
Molecular Function GO:0038023 signaling receptor activity
Biological Process GO:0001525 angiogenesis
Biological Process GO:0038027 apolipoprotein A-I-mediated signaling pathway
Biological Process GO:0043277 apoptotic cell clearance
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0033627 cell adhesion mediated by integrin
Biological Process GO:0016477 cell migration
Biological Process GO:0098609 cell-cell adhesion
Biological Process GO:0007160 cell-matrix adhesion
Biological Process GO:0035987 endodermal cell differentiation
Biological Process GO:0070371 ERK1 and ERK2 cascade
Biological Process GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
Biological Process GO:0034113 heterotypic cell-cell adhesion
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0050919 negative chemotaxis
Biological Process GO:2000536 negative regulation of entry of bacterium into host cell
Biological Process GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
Biological Process GO:0010888 negative regulation of lipid storage
Biological Process GO:0032369 negative regulation of lipid transport
Biological Process GO:0050748 negative regulation of lipoprotein metabolic process
Biological Process GO:0010745 negative regulation of macrophage derived foam cell differentiation
Biological Process GO:0045785 positive regulation of cell adhesion
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0033690 positive regulation of osteoblast proliferation
Biological Process GO:0051057 positive regulation of small GTPase mediated signal transduction
Biological Process GO:0050764 regulation of phagocytosis
Biological Process GO:0034446 substrate adhesion-dependent cell spreading
Biological Process GO:0046718 symbiont entry into host cell
Biological Process GO:0071604 transforming growth factor beta production

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.