Search Results
Overview
| Uniprot ID | A0A5K1VDW0 |
|---|---|
| Protein Name | Actin-related protein 2/3 complex subunit 5 |
| Gene Name | ARPC5L |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 219 | RNSPVNTKNQAVKER |
Function
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development
Protein Sequence
10
MRQDFQEVEG
20
TREERAEDSA
30
EPGAPPVQER
40
SRRRVQLWRR
50
PGAEPSRDWA
60
PVSQSGRLRL
70
HEDRSPGESH
80
KAVFQNSFSA
90
LPATPRPSLL
100
PALPVPAWPG
110
SGRAAAAARG
120
GGGGGAGSPL
130
PAPEPEPVPS
140
GVEWRSAPER
150
SWLSGRRAPA
160
MARNTLSSRF
170
RRVDIDEFDE
180
NKFVDEQEEA
190
AAAAAEPGPD
200
PSEVDGLLRQ
210
GDMLRAFHAA
220
LRNSPVNTKN
230
QAVKERAQGV
240
VLKVLTNFKS
250
SEIEQAVQSL
260
DRNGIDLLMK
270
YIYKGFEKPT
280
ENSSAVLLQW
290
HEKALAVGGL
300
GSIIRVLTAR
KTV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005885 | Arp2/3 protein complex |
| Cellular Component | GO:0030863 | cortical cytoskeleton |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Biological Process | GO:0034314 | Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.