Search Results

Overview

Uniprot ID	A0A5K1VS82
Protein Name	V-type proton ATPase subunit a
Gene Name	TCIRG1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
236	QIGQKIRKITDCFHC

Function

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase

Protein Sequence

10 MGSMFRSEEV 20 ALVQLFLPTA 30 AAYTCVSQLG 40 ELGLVEFRDL 50 NASVSAFQRR 60 FVVDVRRCEE 70 LEKTFTFLQA 80 EVRRAGLALP 90 LPEGVLLAPP 100 PRDLLRIQEE 110 SDRLAQELRD 120 VRGNQQALRA 130 QLHQLQLHSA 140 VLSQGHGHGP 150 QLAATHTDMP 160 LERTPLLQAP 170 GGPHQDLRVN 180 FVAGAVEPHK 190 AAALERLLWR 200 ACRGFLIASF 210 RETEQQLEDP 220 VTGEPATWTT 230 FLISYWGEQI 240 GQKIRKITDC 250 FHCHVFPFAE 260 QEEARLGALQ 270 QLQQQSHELQ 280 EVLGETERFL 290 SQVLGRVQKL 300 LPPWQVQIRK 310 MKAVYLALNQ 320 CSVSTTHKCL 330 IAEAWCATRD 340 LPTVQQALQD 350 SSSEAGVSAV 360 VHRIPCRDMP 370 PTLVRTNRFT 380 ASFQGIVDAY 390 GVGRYQEVNP 400 APYTIITFPF 410 LFAVMFGDVG 420 HGLLMFLFAL 430 AMVLAENRPA 440 VKTAQNEIWR 450 TFFGGRYLLL 460 LMGLFSVYTG 470 FIYNECFSRA 480 TAIFPSGWSV 490 AAMANQSGWS 500 DTFLAEHPLL 510 TLDPNVTGVF 520 LGPYPFGIDP 530 VWSLAVNHLS 540 FLNSFKMKMS 550 VILGVTHMTF 560 GVVLGVFNHM 570 HFGQWHRLLL 580 ETVPELVFLL 590 ALFGYLVFLI 600 VYKWLRFTAA 610 DAASAPSVLL 620 HFINMFLFSR 630 SATNRPLFPG 640 QEVVQSVLVV 650 LALAMVPILL 660 LGTPLFLRQQ 670 HRRHARRRQL 680 VEDEDKTGLL 690 DASVSVSSQG 700 LDEEKAECPG 710 DREEAEFVAS 720 EVFMHQAIHT 730 IEFCLGCISN 740 TASYLRLWAL 750 SLAHAQLSEV 760 LWAMVMRVGL 770 GLSDEMGVVA 780 VVLVPIFAAF 790 AVMTVAILLV 800 MEGLSAFLHA 810 LRLHWVEFQN 820 KFYAGTGYKL 830 SPFTFAVEDA EHP

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain
Molecular Function	GO:0046961	proton-transporting ATPase activity, rotational mechanism

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.