Search Results
Overview
| Uniprot ID | A0A5K1VU77 |
|---|---|
| Protein Name | Peptidyl-prolyl cis-trans isomerase |
| Gene Name | PPIH |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 137 | KCDWLDGKHVVFGKI |
| 153 | DGLLVMRKIENVPTG |
| 53 | FCTGEFRKDGVPIGY |
Function
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone
Protein Sequence
10
MAVANSSPVN
20
PVVFFDVSIG
30
GQEVGRMKIE
40
LFADVVPKTA
50
ENFRQFCTGE
60
FRKDGVPIGY
70
KGSTFHRVIK
80
DFMIQGGDFV
90
NGDGTGVASI
100
YRGPFADENF
110
KLRHSAPGLL
120
SMANSGPSTN
130
GCQFFITCSK
140
CDWLDGKHVV
150
FGKIIDGLLV
160
MRKIENVPTG
170
PNNKPKLPVV
ISQCGEM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0016018 | cyclosporin A binding |
| Molecular Function | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.