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Overview

Uniprot IDA0A5S6HET4
Protein NameCalcium-transporting ATPase
Gene NameATP2A2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
134 DIRLTSIKSTTLRVD
446 VIKQLMKKEFTLEFS
508 MTPGVKQKIMSVIRE
576 IEVASSVKLCRQAGI
960 RNYLEPGKECVQPAT

Function

Catalyzes the hydrolysis of ATP coupled with the transport of calcium

Protein Sequence

10 MENAHTKTVE 20 EVLGHFGVNE 30 STGLSLEQVK 40 KLKERWGSNE 50 LPAEEGKTLL 60 ELVIEQFEDL 70 LVRILLLAAC 80 ISFERNAENA 90 IEALKEYEPE 100 MGKVYRQDRK 110 SVQRIKAKDI 120 VPGDIVEIAV 130 GDKVPADIRL 140 TSIKSTTLRV 150 DQSILTGESV 160 SVIKHTDPVP 170 DPRAVNQDKK 180 NMLFSGTNIA 190 AGKAMGVVVA 200 TGVNTEIGKI 210 RDEMVATEQE 220 RTPLQQKLDE 230 FGEQLSKVIS 240 LICIAVWIIN 250 IGHFNDPVHG 260 GSWIRGAIYY 270 FKIAVALAVA 280 AIPEGLPAVI 290 TTCLALGTRR 300 MAKKNAIVRS 310 LPSVETLGCT 320 SVICSDKTGT 330 LTTNQMSVCR 340 MFILDKVEGD 350 TCSLNEFTIT 360 GSTYAPIGEV 370 HKDDKPVKCH 380 QYDGLVELAT 390 ICALCNDSAL 400 DYNEAKGVYE 410 KVGEATETAL 420 TCLVEKMNVF 430 DTELKGLSKI 440 ERANACNSVI 450 KQLMKKEFTL 460 EFSRDRKSMS 470 VYCTPNKPSR 480 TSMSKMFVKG 490 APEGVIDRCT 500 HIRVGSTKVP 510 MTPGVKQKIM 520 SVIREWGSGS 530 DTLRCLALAT 540 HDNPMRREEM 550 NLEDSANFIK 560 YETNLTFVGC 570 VGMLDPPRIE 580 VASSVKLCRQ 590 AGIRVIMITG 600 DNKGTAVAIC 610 RRIGIFGQDE 620 DVTSKAFTGR 630 EFDELNPSAQ 640 REACLNARCF 650 ARVEPSHKSK 660 IVEFLQSFDE 670 ITAMTGDGVN 680 DAPALKKSEI 690 GIAMGSGTAV 700 AKTASEMVLA 710 DDNFSTIVAA 720 VEEGRAIYNN 730 MKQFIRYLIS 740 SNVGEVVCIF 750 LTAALGFPEA 760 LIPVQLLWVN 770 LVTDGLPATA 780 LGFNPPDLDI 790 MNKPPRNPKE 800 PLISGWLFFR 810 YLAIGCYVGA 820 ATVGAAAWWF 830 IAADGGPRVT 840 FYQLSHFLQC 850 KEDNPDFEGV 860 DCAVFESPYP 870 MTMALSVLVT 880 IEMCNALNSL 890 SENQSLLRMP 900 PWENIWLVGS 910 ICLSMSLHFL 920 ILYVEPLPLI 930 FQITPLNLTQ 940 WLMVLKISLP 950 VILMDETLKF 960 VARNYLEPGK 970 ECVQPATKSC 980 SFSACTDGIS 990 WPFVLLIMPL 1000 VIWVYSTDTN FSDMFWS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0033017 sarcoplasmic reticulum membrane
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0005388 P-type calcium transporter activity
Biological Process GO:1990036 calcium ion import into sarcoplasmic reticulum
Biological Process GO:0003012 muscle system process
Biological Process GO:0008016 regulation of heart contraction
Biological Process GO:0006937 regulation of muscle contraction

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.