Search Results

Overview

Uniprot ID	A0A6J1RYV4
Protein Name	Eukaryotic translation initiation factor 3 subunit A
Gene Name	LOC113203576
Organism	Frankliniella occidentalis

Kla Sites from experimental identification

Position	Flanking peptide
353	TDKSPLEKAQRLATL
374	PTRASLLKDIVRVNV

Function

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation

Protein Sequence

10 MARYGQRPEN 20 ALKRANEFIE 30 VGKPARALDT 40 LYEVFKNKKW 50 ACNWSETVLE 60 PIMFKYLDLC 70 VELKKSHIAK 80 EGLFQYRNMF 90 QSVNVGSLEN 100 VIRGYLRTAE 110 ERTESAREQS 120 QQAVIDVEDL 130 EMIATPESIL 140 LSAVSGEDAQ 150 DRSDRTILTP 160 WVKFLWESYC 170 QCLELLRTNA 180 HVETLYHDIA 190 RMAFNFCLKY 200 NRKTEFRKLC 210 DKLRKHLEDI 220 SKLPAQVSNV 230 SISKPETQQL 240 NLETRLVQLD 250 SAIHMELWQE 260 AYKATEDIHG 270 LMNMSKKSPV 280 PKTMANYYQK 290 LALVFWKANN 300 CLFHAAALFK 310 LFQLSKEMKK 320 NITPEELQRM 330 ACRVLLATLS 340 IPLPSAHPEF 350 DRFIETDKSP 360 LEKAQRLATL 370 LGLPQPPTRA 380 SLLKDIVRVN 390 VVGLAAPQLQ 400 DLYSWLEVEF 410 DPLNLCSRVQ 420 SVVESLQAEE 430 NSQLVQYTPA 440 LQDVTLVRLI 450 RQVSQVYQTV 460 KIARLLELAR 470 FTDTMHLERL 480 LVDCVRHNDM 490 QIRIDHGAEC 500 IHFGMDLAES 510 QREDHPEGPT 520 LQSMPSEQVR 530 NQLINMACVL 540 SRSINCINPA 550 KKKVEREVLR 560 HKMVERYHAT 570 KVEEHAQILK 580 RHKIIEDRKE 590 YLERINILRE 600 EEAARRQDEL 610 ARMQMAQEQK 620 RLAMELEERE 630 RKRQENEIQQ 640 IKDRHLKEKM 650 QQISQTAHGQ 660 KILKKLDEDA 670 LQNMDAEQIT 680 AREMEELQKE 690 RRDMMQKLKS 700 QEKKMDYFIR 710 ATRIEEIPLL 720 NKSFEENQIK 730 DRAFWEQQEK 740 ERIAKLVEER 750 ELAVQNRERL 760 ARMYDDKEEF 770 LSQLMNERNS 780 TYEDKMAAYN 790 VLLEAKRAER 800 LADRKAKRKT 810 ERREKYHRQK 820 REEQERKEQE 830 EREEKERKER 840 EEREEKERKE 850 REEREERERK 860 EREEREEENK 870 KRQEALDRQA 880 KIQQERMEEI 890 ERRSREAEKA 900 APSATPAAST 910 WRRGGDRDGD 920 DRRPDDRRGD 930 DTWRRGDSAK 940 EGGAGGGAGG 950 AWRPTRLREG 960 GDWRTKEAAE 970 REAGARDAAP 980 REGGDRDREG 990 GERVERGGRG 1000 GFDRDGPRGF 1010 DRDREGGRGG 1020 FDRDRDSGRG 1030 GFDRDRDGGR 1040 GFDRDREGGR 1050 GGYDRDGGRG 1060 FDRGGDRFGR 1070 DRPAADMGSW 1080 RRGPAPGGED 1090 DDDRRGGPRR 1100 DMRRDDRRDD 1110 RRDDRPREAG 1120 AWRKEAAAPA PADAPSKEE

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0016282	eukaryotic 43S preinitiation complex
Cellular Component	GO:0033290	eukaryotic 48S preinitiation complex
Cellular Component	GO:0071540	eukaryotic translation initiation factor 3 complex, eIF3e
Cellular Component	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m
Cellular Component	GO:0043614	multi-eIF complex
Molecular Function	GO:0003729	mRNA binding
Molecular Function	GO:0003743	translation initiation factor activity
Biological Process	GO:0001732	formation of cytoplasmic translation initiation complex
Biological Process	GO:0002188	translation reinitiation

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.