Search Results
Overview
| Uniprot ID | A0A6J1S5C5 |
|---|---|
| Protein Name | ADP/ATP translocase |
| Gene Name | LOC113203461 |
| Organism | Frankliniella occidentalis |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 148 | RLAADIGKGDGRQFN |
| 162 | NGLADCLKKTFKSDG |
| 166 | DCLKKTFKSDGLIGM |
| 246 | MMQAGRKKADIMYTG |
| 263 | DCWAKIAKNEGTGAF |
| 50 | STQIAADKQYKGIVD |
| 53 | IAADKQYKGIVDCFV |
| 64 | DCFVRIPKEQGFASF |
Function
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane
Protein Sequence
10
MANTDALSFF
20
KDFMAGGISA
30
AVSKTAVAPI
40
ERVKLLLQVQ
50
AASTQIAADK
60
QYKGIVDCFV
70
RIPKEQGFAS
80
FWRGNLANVI
90
RYFPTQALNF
100
AFKDIYKQIF
110
LGGVDKNTQF
120
WRYFAGNLAS
130
GGAAGASSLC
140
IVYPLDFART
150
RLAADIGKGD
160
GRQFNGLADC
170
LKKTFKSDGL
180
IGMYRGFGVS
190
VQGIIIYRAA
200
YFGFFDTAKG
210
MLPNPKTTPF
220
LVSWAIAQTV
230
TTVAGIASYP
240
FDTVRRRMMM
250
QAGRKKADIM
260
YTGTLDCWAK
270
IAKNEGTGAF
280
FKGAFSNVLR
290
GTGGALVLVF
YDEIKKLI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Biological Process | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway |
| Molecular Function | GO:0005471 | ATP:ADP antiporter activity |
| Biological Process | GO:0140021 | mitochondrial ADP transmembrane transport |
| Biological Process | GO:1990544 | mitochondrial ATP transmembrane transport |
Reference
[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.