Search Results

Overview

Uniprot ID	A0A6J1S7P8
Protein Name	H(+)-transporting two-sector ATPase
Gene Name	LOC113203977
Organism	Frankliniella occidentalis

Kla Sites from experimental identification

Position	Flanking peptide
160	ENTLVKHKIILPPKA

Function

Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment

Protein Sequence

10 MLPKIRDEDK 20 ESRFGYVYAV 30 SGPVVTAERM 40 SGSAMYELVR 50 VGYHELVGEI 60 IRLEGDMATI 70 QVYEETSGVT 80 VGDPVLRTGK 90 PLSVELGPGI 100 LGSIFDGIQR 110 PLKDISELAG 120 SIYIPKGVNV 130 PALSRAASWE 140 FNPLSIKIGS 150 HMTGGDLYGV 160 VHENTLVKHK 170 IILPPKAKGT 180 VTYIAEPGNY 190 TVDDVILETE 200 FDGEKSKFTM 210 LQVWPVRQPR 220 PVTEKLPANY 230 PLLTGQRVLD 240 SLFPCVQGGT 250 TAIPGAFGCG 260 KTVISQALSK 270 YSNSDVIVYV 280 GCGERGNEMS 290 EVLRDFPELS 300 VEIDGQTESI 310 MKRTALVANT 320 SNMPVAAREA 330 SIYTGITLSE 340 YFRDMGYNVS 350 MMADSTSRWA 360 EALREISGRL 370 AEMPADSGYP 380 AYLGARLASF 390 YERAGRVKCL 400 GNPDREGSVS 410 IVGAVSPPGG 420 DFSDPVTSAT 430 LGIVQVFWGL 440 DKKLAQRKHF 450 PSINWLISYS 460 KYMRALDDFY 470 DKNFPEFVPL 480 RTKVKEILQE 490 EEDLSEIVQL 500 VGKASLAEAD 510 KITLEVAKLL 520 KDDFLQQNSY 530 SAYDRFCPFY 540 KTSGMLKNMI 550 AFYDMSRHAV 560 ESTAQSENKI 570 TWNVIRDSMG 580 QIMYQLSSMK 590 FKDPHKDGEA 600 KIKADFEQLH 610 EDLQQAFRNL ED

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005765	lysosomal membrane
Cellular Component	GO:0033180	proton-transporting V-type ATPase, V1 domain
Molecular Function	GO:0005524	ATP binding
Molecular Function	GO:0016887	ATP hydrolysis activity
Molecular Function	GO:0046961	proton-transporting ATPase activity, rotational mechanism
Biological Process	GO:0046034	ATP metabolic process

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.