Search Results
Overview
| Uniprot ID | A0A6J1SBL9 |
|---|---|
| Protein Name | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial |
| Gene Name | LOC113205291 |
| Organism | Frankliniella occidentalis |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 176 | GNVHKRGKVGVVSRS |
| 301 | DKIDALEKAGVVVTR |
| 47 | IIQGFTGKQGTFHGK |
| 71 | VGGSTPGKGGQKNLD |
Function
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits
Protein Sequence
10
MALFVRSLPC
20
VGALRQLGGV
30
RTNYSDTRKF
40
LKLTAETKVI
50
IQGFTGKQGT
60
FHGKQAIEYG
70
TKVVGGSTPG
80
KGGQKNLDLP
90
VFNTVKEARD
100
SVGADATFVA
110
VPPPVGANAI
120
LEAIDAEIPL
130
IVCITEGIPQ
140
HDMVRVKHRL
150
LRQNKSRLIG
160
PNCPGIIAPE
170
RCKIGIMPGN
180
VHKRGKVGVV
190
SRSGTLTYEA
200
VHQTTRAGLG
210
QTLCIGIGGD
220
PFNGTDFIDC
230
LEVFLNDPET
240
EGIILIGEIG
250
GVQEENAAKY
260
LIEHNSGPNA
270
KPVVSFIAGL
280
TAPPGRRMGH
290
AGAIISGGKG
300
GAQDKIDALE
310
KAGVVVTRSP
320
AQMGNELLKL
MLRK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0009361 | succinate-CoA ligase complex (ADP-forming) |
| Molecular Function | GO:0000166 | nucleotide binding |
| Molecular Function | GO:0004775 | succinate-CoA ligase (ADP-forming) activity |
| Molecular Function | GO:0004776 | succinate-CoA ligase (GDP-forming) activity |
| Biological Process | GO:0006099 | tricarboxylic acid cycle |
Reference
[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.