Search Results

Overview

Uniprot IDA0A6J1SDU7
Protein NameEukaryotic translation initiation factor 3 subunit C
Gene NameLOC113206813
OrganismFrankliniella occidentalis

Kla Sites from experimental identification

Position Flanking peptide
527 LCKFIYDKDQSDRLR

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation

Protein Sequence

10 MSRFFATGSD 20 SDSDSSSEEE 30 QIIRQPTATF 40 TFSDEEEDTK 50 RVVRSAKEKR 60 YEEITNLIKQ 70 IRNYKKIKDM 80 SSLLSSFEDL 90 MRAYTKALPV 100 ISKEENGVTP 110 RFYLRCLVEV 120 EDFVNEVWED 130 REGRKNMSKN 140 NSKSLTSLRQ 150 KMRKYNKDFE 160 EEITKFRANP 170 DQADEEEEEE 180 KDQDDDSSDD 190 EDSHPVVSKK 200 PSVEPVPEPK 210 KKATGGDDDD 220 DGSSDSYWGS 230 DSESSSDSSE 240 DESQYTSVRE 250 RFLKKATDKD 260 DDEKKEKKDR 270 KEDRKKSKPK 280 RKEEDSDGEG 290 EWETVKGGVA 300 IPSEKPKMFA 310 KDAEINIDLV 320 VKKLNEIVAA 330 RGKKRTDRRE 340 QIELLHELLI 350 VSEQHNLGSA 360 VSIKIKFAIV 370 SSIFDYNPKV 380 SDAMKPEYWA 390 KLLEQIIDMM 400 DRLINAKNVI 410 INESILEDNE 420 NYESPPYQLR 430 GCVLTVMERL 440 DEEFTKLLKE 450 CDPHSNEYVE 460 RLKDEKRVSS 470 IIDKVQEYLE 480 SQTDIDAELC 490 RIYMRKIEHL 500 YYKFDPQVLQ 510 QKQGLVPADT 520 VTGVQIMDKL 530 CKFIYDKDQS 540 DRLRTRAILS 550 HVYHHALHDN 560 WFQARDLILM 570 SHLQENIQHA 580 DPPTQILYNR 590 TMAHLGLCAF 600 RHANIKDAHN 610 CLVDLMMTGK 620 MKELLAQGLL 630 PTRQNDRTKE 640 QEKVEKQRQM 650 PFHMHINLEL 660 LECVYMVSAM 670 LIEIPYMAEH 680 EFDARRRMIS 690 KTFYQQLRSS 700 ERQSLLGPPE 710 SMREHVVAAS 720 KAMRNGNWLA 730 CRNFIINEKM 740 NAKVWDLFYQ 750 ADDVRTMLTK 760 LIREEALRTY 770 LFTYSHVYDS 780 ISMATLATTF 790 ELEPSVVHSI 800 ISKMIINEEL 810 MASLDDPTHT 820 VVMHRSEPSR 830 LQSLALQLTD 840 KVNSLVDYNE 850 RVFETKQGFF 860 NRGGNQGRDF 870 RDRQNYDRRG 880 QDWGRQRRER GERAY

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016282 eukaryotic 43S preinitiation complex
Cellular Component GO:0033290 eukaryotic 48S preinitiation complex
Cellular Component GO:0005852 eukaryotic translation initiation factor 3 complex
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003743 translation initiation factor activity
Molecular Function GO:0031369 translation initiation factor binding
Biological Process GO:0001732 formation of cytoplasmic translation initiation complex

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.