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Overview

Uniprot IDA0A6J1SKX3
Protein NameTubulin beta chain
Gene NameLOC113208689
OrganismFrankliniella occidentalis

Kla Sites from experimental identification

Position Flanking peptide
58 YNEASGGKYVPRAIL

Function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Protein Sequence

10 MREIVHIQAG 20 QCGNQIGAKF 30 WEIISDEHGI 40 DPTGAYHGDS 50 DLQLDRINVY 60 YNEASGGKYV 70 PRAILVDLEP 80 GTMDSVRSGP 90 FGQIFRPDNF 100 VFGQSGAGNN 110 WAKGHYTEGA 120 ELVDAVLDVV 130 RKEAEGCDCL 140 QGFQLTHSLG 150 GGTGSGMGTL 160 LISKIREEYP 170 DRIMNTYSVV 180 PSPKVSDTVV 190 EPYNATLSVH 200 QLVENTDETY 210 CIDNEALYDI 220 CFRTLKLSTP 230 TYGDLNHLVS 240 LTMSGVTTCL 250 RFPGQLNADL 260 RKLAVNMVPF 270 PRLHFFMPGF 280 APLTARGSQQ 290 YRALTVPELT 300 QQMFDAKNMM 310 AACDPRHGRY 320 LTVAAIFRGR 330 MSMKEVDEQM 340 LNIQNKNSSY 350 FVEWIPNNVK 360 TAVCDIPPRG 370 LKMSATFIGN 380 STAIQELFKR 390 ISEQFTAMFR 400 RKAFLHWYTG 410 EGMDEMEFTE 420 AESNMNDLVS 430 EYQQYQEATA 440 DEDAEFDEDQ EEVEQD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005874 microtubule
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0003924 GTPase activity
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0005200 structural constituent of cytoskeleton
Biological Process GO:0007017 microtubule-based process

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.