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Overview

Uniprot IDA0A6J1SLY4
Protein NameATP synthase subunit b
Gene NameLOC113208796
OrganismFrankliniella occidentalis

Kla Sites from experimental identification

Position Flanking peptide
169 REFEDSEKKQIRENI
220 NTAYTEAKKRLDYQL
263 TQEAETLKKCISDLK
57 VPRIVPLKTEGPERD
74 NFPRPVVKQHPDPVR

Function

Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements

Protein Sequence

10 MLSRLATRAA 20 QPLISRPAVL 30 GIRQASSEPA 40 KTVTSDVDPY 50 AGLEDPISKV 60 PRIVPLKTEG 70 PERDLVNFPR 80 PVVKQHPDPV 90 RLGFLPEEWF 100 DIFYKKTGVS 110 GPYVFGASFL 120 TYLLSKEIYV 130 LEHNFYNGIS 140 FVMILMILHH 150 KLGPSIAKLT 160 DKEIDQWLAD 170 TREFEDSEKK 180 QIRENIKEIH 190 AYLSNLDVFK 200 DLAAARRETA 210 AAALEATYRE 220 WSNTAYTEAK 230 KRLDYQLELT 240 NVERRISQKN 250 MSSWITENVM 260 KSITPTQEAE 270 TLKKCISDLK SLSASA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0045259 proton-transporting ATP synthase complex
Molecular Function GO:0046933 proton-transporting ATP synthase activity, rotational mechanism

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.