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Overview

Uniprot IDA0A6J1SNI0
Protein NameLarge ribosomal subunit protein bL12m
Gene NameLOC113209162
OrganismFrankliniella occidentalis

Kla Sites from experimental identification

Position Flanking peptide
116 VKNSFNVKIVKFDEK
130 KQKVALIKCVKGLVE

Function

As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation. When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription. Required for POLRMT stability

Protein Sequence

10 MQAVRSSLRR 20 CLSQWDAVQN 30 CCGTIAARHM 40 SAEAMPAPTP 50 DNAPKMYPLK 60 IEKIVDEIAG 70 LTLVEVADLS 80 ELLKKRLNLP 90 DAPAMPMGGF 100 MPVGAAAAAA 110 PEEAKEEAVK 120 NSFNVKIVKF 130 DEKQKVALIK 140 CVKGLVEGMN 150 LVQAKKFIES 160 APVVLKENIE 170 KEEAEKLKAE 180 LTAIGAEVVL E

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005762 mitochondrial large ribosomal subunit
Molecular Function GO:0003729 mRNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0006412 translation

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.