Overview
| Uniprot ID | A0A6J1SS99 |
|---|
| Protein Name | Large ribosomal subunit protein uL18 |
|---|
| Gene Name | LOC113209077 |
|---|
| Organism | Frankliniella occidentalis |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 188 |
PGFDSESKEFNADVH |
| 220 |
EEDDEAYKRQFSQYI |
| 41 |
KRLIAQDKNKYNTPK |
| 5 |
***MGFVKVVKNKQY |
Function
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel
Protein Sequence
10
MGFVKVVKNK
20
QYFKRYQVKF
30
KRRREGKTDY
40
FARKRLIAQD
50
KNKYNTPKYR
60
LVVRFSNRDI
70
TCQVAYSRIE
80
GDKILCAAYA
90
HELPQYGVKV
100
GLTNYAAAYC
110
TGLLLARRLL
120
SQLGLDKLYI
130
GSTEVTGEEF
140
NVEAVEDGPG
150
AFRCYLDVGL
160
MRTSTGARVF
170
GAMKGAVDGG
180
LNIPHSTKRF
190
PGFDSESKEF
200
NADVHRQHIF
210
GQHVAEYMRQ
220
LAEEDDEAYK
230
RQFSQYIKLG
240
LNADAIEGLY
250
KKAHEAIRAN
260
PARKTVAKKA
270
HPKKRWTEKK
280
LTREQRQGKV
290
AAAKAEWLKK
IEAGEVE
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0022625 |
cytosolic large ribosomal subunit |
| Molecular Function |
GO:0008097 |
5S rRNA binding |
| Molecular Function |
GO:0003735 |
structural constituent of ribosome |
| Biological Process |
GO:0000027 |
ribosomal large subunit assembly |
| Biological Process |
GO:0006412 |
translation |
Reference
[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.