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Overview

Uniprot IDA0A6J1SST6
Protein NameElectron transfer flavoprotein subunit beta
Gene NameLOC113210262
OrganismFrankliniella occidentalis

Kla Sites from experimental identification

Position Flanking peptide
108 HISKILAKLAQEEKA
17 RVIDYAVKIRVKPDK
172 DGGLENIKVKLPAVL
210 PLKKITPKDLGVDIS
248 DTLISKLKESGHV**

Function

Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase. Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role

Protein Sequence

10 MARVLVGVKR 20 VIDYAVKIRV 30 KPDKKGVVTE 40 GVKHSMNPFD 50 EIAVEEAVKM 60 KEKKLASEVV 70 AVSCGPSQAQ 80 ETLRTALAMG 90 VDRAIHVEVP 100 AGEYETLQPI 110 HISKILAKLA 120 QEEKADIVIL 130 GKQAIDDDSN 140 QTAQMTAGVL 150 DWPQATFASK 160 IEKKDSELHV 170 TREIDGGLEN 180 IKVKLPAVLS 190 ADLRLNEPRY 200 ATLPNIMKAK 210 KKPLKKITPK 220 DLGVDISPRI 230 EIISVEEPPV 240 RQAGSVVPDV 250 DTLISKLKES GHV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005759 mitochondrial matrix
Molecular Function GO:0009055 electron transfer activity
Biological Process GO:0009063 amino acid catabolic process
Biological Process GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.