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Overview

Uniprot IDA0A6J1TFY5
Protein NameMitochondrial import inner membrane translocase subunit TIM44
Gene NameLOC113216786
OrganismFrankliniella occidentalis

Kla Sites from experimental identification

Position Flanking peptide
358 MGARFDSKILDIKDV

Function

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source

Protein Sequence

10 MIRHIPSVMK 20 PWVVADRFPT 30 HNRWIYPSIS 40 SFSRLPTSNY 50 EVTRPYSNQG 60 GRPSLWGRFM 70 ENIKQEMTKN 80 KEMKESLKKF 90 REERQKLEQS 100 EALRKARQKF 110 ESVESEASKS 120 SEVLKGKLGA 130 FKGKVQEAMG 140 EVGKTEFAKK 150 AGQITEDIGK 160 SAKEAAEKIS 170 EQGQTLGKSG 180 AFKTVSEAAQ 190 VVKEELDTRG 200 RVYQAPGKLR 210 KRREGADDEE 220 FKPVEPNTEA 230 LGMELHKDSK 240 FYQSWQNFKD 250 NNQYINKVLD 260 WKMKYDESDN 270 PLVRASRAVT 280 ERVTDMMGGL 290 FQKTELSETL 300 TEICKVDPNF 310 DRLQFLRHCE 320 TDIIPNVLEA 330 MVRGDLEILK 340 DWCHEGPYNI 350 LSTPIKQAQK 360 MGARFDSKIL 370 DIKDVDLSMG 380 KMMDQGPVLV 390 ISFQSQQIMC 400 LRDSKGAVLE 410 GDPEKVLRVH 420 YVWVLCRDMT 430 ELDPRAAWRL 440 LDLSANSQEQ LL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0051087 protein-folding chaperone binding
Biological Process GO:0030150 protein import into mitochondrial matrix

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.