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Overview

Uniprot IDA0A6J1TVB8
Protein NameNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
Gene NameLOC113218417
OrganismFrankliniella occidentalis

Kla Sites from experimental identification

Position Flanking peptide
60 MSCQRLKKIYLEQKS

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes

Protein Sequence

10 MSKAVAPPQD 20 LPPPGGFGKV 30 SYEKVPHRTF 40 FNGSRIALTA 50 FVSYAVGSVL 60 YTMSCQRLKK 70 IYLEQKSGQI 80 ATQPFLLAER 90 DRQLLRQMRR 100 NRDAEAELMK 110 DVEGWEVGTL 120 YGTPVFSTLG 130 ENEWVEYSAQ 140 SYYAHADPQD 150 RMEYENSSHW L

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0045271 respiratory chain complex I
Biological Process GO:0022904 respiratory electron transport chain

Reference

[1] An D, Song L, Li Y, Shen L, Miao P et al.. Comprehensive analysis of lysine lactylation in Frankliniella occidentalis.. Front Genet 13:1014225. 2022. PMID: 36386791.