Search Results
Overview
| Uniprot ID | A0A6Q8PHQ0 |
|---|---|
| Protein Name | Histidine--tRNA ligase, cytoplasmic |
| Gene Name | HARS1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 60 | KFVLKTPKALEEKIR |
Function
Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Plays a role in axon guidance
Protein Sequence
10
MAERAALEEL
20
VKLQGERVRG
30
LKQQKASAEL
40
IEEEVAKLLK
50
LKAQLGPDES
60
KQKFVLKTPK
70
ALEEKIRTTE
80
TQVLVASAQK
90
KLLEERLKLV
100
SELWDAGIKA
110
ELLYKKNPKL
120
LNQLQYCEEA
130
GIPLVAIIGE
140
QELKDGVIKL
150
RSVTSREEVD
160
VRREDLVEEI
170
KRRTGQPLCI
C
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0004821 | histidine-tRNA ligase activity |
| Biological Process | GO:0006418 | tRNA aminoacylation for protein translation |
Reference
PMID: N/A