Search Results
Overview
| Uniprot ID | A0A8D0PHF2 |
|---|---|
| Protein Name | DCN1-like protein |
| Gene Name | DCUN1D5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 23 | VAEDGSLKKCKISSY |
| 8 | MPVKKKRKSSGVAAA |
Function
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth
Protein Sequence
10
MPVKKKRKSS
20
GVAAAVAEDG
30
SLKKCKISSY
40
CRSQPPARLI
50
SGEEHFSSKK
60
CLAWFYEYAG
70
PDEVVGPEGM
80
EKFCEDIGVE
90
PENIIMLVLA
100
WKLEAESMGF
110
FTKEEWLKGM
120
TSLQCDCTEK
130
LQNKFDFLRS
140
QLNDISSFKN
150
IYRYAFDFAR
160
DKDQRSLDID
170
TAKSMLALLL
180
GRTWPLFSVF
190
YQYLEGLFFL
200
MNLLSGRKFV
210
KRHSKNCCEE
220
NANLLIPTHV
230
QANEIVKKMQ
TF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005819 | spindle |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.