Search Results

Overview

Uniprot IDA0A8D0RJA4
Protein NameVesicle-trafficking protein SEC22b
Gene NameSEC22B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
100 CEAAFPKKLAFAYLE
142 TYIQKTKKLYIDSRA
196 NNLSSLSKKYRQDAK
43 QAKQLFRKLNEQSPT

Function

SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER

Protein Sequence

10 MVLLTMIARV 20 ADGLPLAASM 30 QEDEQSGRDL 40 QQYQSQAKQL 50 FRKLNEQSPT 60 RCTLEAGAMT 70 FHKGNFNNTV 80 SPNHIFLDPS 90 YIIEQGVCYL 100 VLCEAAFPKK 110 LAFAYLEDLH 120 SEFDEQHGKK 130 VPTVSRPYSF 140 IEFDTYIQKT 150 KKLYIDSRAR 160 RNLGSINTEL 170 QDVQRIMVAN 180 IEEVLQRGEA 190 LSALDSKANN 200 LSSLSKKYRQ 210 DAKYLNMRST 220 YAKLAAVAVF 230 FIMLIVYVRF WWL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Cellular Component GO:0012507 ER to Golgi transport vesicle membrane
Cellular Component GO:0000139 Golgi membrane
Cellular Component GO:0042470 melanosome
Cellular Component GO:0031201 SNARE complex
Molecular Function GO:0005484 SNAP receptor activity
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:1902902 negative regulation of autophagosome assembly
Biological Process GO:0045732 positive regulation of protein catabolic process
Biological Process GO:0015031 protein transport
Biological Process GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Biological Process GO:0048280 vesicle fusion with Golgi apparatus

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.