Search Results
Overview
| Uniprot ID | A0A8D0YET4 |
|---|---|
| Protein Name | Calcium uniporter protein |
| Gene Name | MCU |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 109 | TYHVRPPKRDLLSHE |
| 156 | IERLEDLKEQLAPLE |
| 164 | EQLAPLEKVRIEISR |
| 261 | KSRFDLEKYNQLKDA |
Function
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways
Protein Sequence
10
CILFNLGVVY
20
CSTVVPSDDV
30
TVVYQNGLPV
40
ISVRLPSRRE
50
RCQFTLKPIS
60
DSVGVFLRQL
70
QEEDRGIDRV
80
AIYSPDGVRV
90
AASTGIDLLL
100
LDDFKLVIND
110
LTYHVRPPKR
120
DLLSHENAAT
130
LNDVKTLVQQ
140
LYTTLCIEQH
150
QLNKERELIE
160
RLEDLKEQLA
170
PLEKVRIEIS
180
RKAEKRTTLV
190
LWGGLAYMAT
200
QFGILARLTW
210
WEYSWDIMEP
220
VTYFITYGSA
230
MAMYAYFVMT
240
RQEYVYPEAR
250
DRQYLLFFHK
260
GAKKSRFDLE
270
KYNQLKDAIA
280
QAEMDLKRLR
290
DPLQVHLPLR
QIGEKD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Molecular Function | GO:0005262 | calcium channel activity |
| Molecular Function | GO:0015292 | uniporter activity |
| Biological Process | GO:0051560 | mitochondrial calcium ion homeostasis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.