Search Results
Overview
| Uniprot ID | A0A8D0YSB2 |
|---|---|
| Protein Name | Dihydropyrimidinase-related protein 2 |
| Gene Name | DPYSL2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 257 | YITKVMSKSAAEVIA |
| 269 | VIAQARKKGTVVYGE |
| 471 | SGRYIPRKPFPDFVY |
| 519 | VTPASSAKTSPAKQQ |
| 524 | SAKTSPAKQQAPPVR |
Function
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis
Protein Sequence
10
MARPGLSQTM
20
IASDRLLIKG
30
GKIVNDDQSF
40
YADIYMEDGL
50
IKQIGENLIV
60
PGGVKTIEAH
70
SRMVIPGGID
80
VHTRFQMPDQ
90
GMTSADDFFQ
100
GTKAALAGGT
110
TMIIDHVVPE
120
PGTSLLSAFD
130
QWREWADSKS
140
CCDYSLHVDI
150
TEWHKGIQEE
160
MEALVKDHGV
170
NSFLVYMAFK
180
DRFQLTDSQI
190
YEVLSVIRDI
200
GAIAQVHAEN
210
GDIIAEEQQR
220
ILDLGITGPE
230
GHVLSRPEEV
240
EAEAVNRSIT
250
IANQTNCPLY
260
ITKVMSKSAA
270
EVIAQARKKG
280
TVVYGEPITA
290
SLGTDGSHYW
300
SKNWAKAAAF
310
VTSPPLSPDP
320
TTPDFLNSLL
330
SCGDLQVTGS
340
AHCTFNTAQK
350
AVGKDNFTLI
360
PEGTNGTEER
370
MSIIWDKAVV
380
TGKMDENQFV
390
AVTSTNAAKV
400
FNLYPRKGRI
410
AVGSDADLVI
420
WDPDSVKTIS
430
AKTHNSSLEY
440
NIFEGMECRG
450
SPLVVISQGK
460
IVLEDGTLHV
470
TEGSGRYIPR
480
KPFPDFVYKR
490
IKARSRLAEL
500
RGVPRGLYDG
510
PVCEVSVTPK
520
TVTPASSAKT
530
SPAKQQAPPV
540
RNLHQSGFSL
550
SGAQIDDNIP
560
RRTTQRIVAP
570
PGGRANITSL
G
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0120025 | plasma membrane bounded cell projection |
| Molecular Function | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0007399 | nervous system development |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.