Search Results
Overview
| Uniprot ID | A0A8D1AA90 |
|---|---|
| Protein Name | Carnitine O-palmitoyltransferase 2, mitochondrial |
| Gene Name | CPT2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 189 | RSDTATFKRLIRLVP |
| 510 | RPASVFTKRCSEAFV |
Function
Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters
Protein Sequence
10
MMARLLLRAW
20
PRDLAVGLAA
30
PCRTLSAGFE
40
PGQYLQRSIV
50
PTMHFQDSLP
60
RLPIPKLEDT
70
MRRYLSAQKP
80
LLDDGQFRKT
90
EELCKNFENG
100
IGKKLHEQLV
110
AQDKQNKHTS
120
YISGPWFDMY
130
LTARNPIVLN
140
FNPFMAFHPD
150
PKSEYNDQLT
160
RATNLTVSAL
170
RFLKALRAGL
180
LEPEVFHLNP
190
ARSDTATFKR
200
LIRLVPSALS
210
WYGAYLVKAY
220
PLDMSQYFRL
230
FNSTRLPRPR
240
RDELFTDDKA
250
RHLLVLRKGH
260
FYVFDVLDQD
270
GKIVSASEIQ
280
AHLKYILSDR
290
SLAPEFPLAY
300
LTSEDRDIWA
310
GLRQKLVQGG
320
NEETLRRVDA
330
AVFCLCLDDF
340
PVKDLIHLSH
350
SMLHGDGTNR
360
WFDKSFNLIL
370
AEDGTAAVHF
380
EHAWGDGVAV
390
LRFLNEVFKD
400
STQAPAVTPQ
410
SPPARTDSSR
420
AVQKLSFKLD
430
DAVKAGISAA
440
KAKFDATVKT
450
LTIDCIQFQR
460
GGKEFLKGQK
470
VSPDSVAQLA
480
FQMAFLRQYG
490
QTVATYESCS
500
TAAFKHGRTE
510
TIRPASVFTK
520
RCSEAFVREP
530
SKHSAAALRQ
540
MVAECSEYHN
550
QLTREAAMGQ
560
GFDRHLFALR
570
NLAKAKGIAL
580
PELYLDPAYK
590
QINHNILSTS
600
TLSSPAVNLG
610
GFAPVVPDGF
620
GIGYAVHNNW
630
IGCNVSAYQS
640
RNAREFLQCV
650
EKALEDMFDA
FEGKAIKT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0004095 | carnitine O-palmitoyltransferase activity |
| Biological Process | GO:0009437 | carnitine metabolic process |
| Biological Process | GO:0006853 | carnitine shuttle |
| Biological Process | GO:0006635 | fatty acid beta-oxidation |
| Biological Process | GO:0001676 | long-chain fatty acid metabolic process |
| Biological Process | GO:0120162 | positive regulation of cold-induced thermogenesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.