Search Results
Overview
| Uniprot ID | A0A8D1BSI8 |
|---|---|
| Protein Name | Midkine |
| Gene Name | MDK |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 78 | RVPCNWKKEFGADCK |
| 87 | FGADCKYKFESWGAC |
Function
Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration
Protein Sequence
10
MQRRGFLLLA
20
LFALLALTDA
30
VAKKKDKVKK
40
GGPGSECAEW
50
TWGPCTPSSK
60
DCGVGFREGT
70
CGAQTQRVRC
80
RVPCNWKKEF
90
GADCKYKFES
100
WGACDGGTGT
110
KARQGTLKKA
120
RYNAQCQETI
130
RVTKPCTPKT
140
KAKAKASFLT
150
HSSPGGQQGR
160
GGSAHFSAKK
GKGKD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005576 | extracellular region |
| Molecular Function | GO:0008201 | heparin binding |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0051781 | positive regulation of cell division |
| Molecular Function | GO:0008083 | growth factor activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.