Search Results
Overview
| Uniprot ID | A0A8D1DJI5 |
|---|---|
| Protein Name | T-complex protein 1 subunit alpha |
| Gene Name | TCP1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 112 | KNADELVKQKIHPTS |
| 114 | ADELVKQKIHPTSVI |
| 129 | SGYRLACKEAVRYIS |
| 202 | VNSINILKAHGRSQT |
| 275 | QRESDITKERIQKIL |
| 368 | DDELILIKNTKARTS |
| 502 | NGKPRDNKQAGVFEP |
| 513 | VFEPTIVKVKSLKFA |
| 535 | LRIDDLIKLHPESKD |
| 544 | HPESKDDKHGGYEDA |
Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia
Protein Sequence
10
AARMEGPLSV
20
FGDRSTGEAI
30
RSQNVMAAAS
40
IANIVKSSLG
50
PVGLDKMLVD
60
DIGDVTITND
70
GATILKLLEV
80
EHPAAKVLCE
90
LADLQDKEVG
100
DGTTSVVIIA
110
AELLKNADEL
120
VKQKIHPTSV
130
ISGYRLACKE
140
AVRYISENLI
150
INTDELGRDC
160
LINAAKTSMS
170
SKIIGINGDF
180
FANMVVDAVL
190
AIKYTDVRGQ
200
PRYPVNSINI
210
LKAHGRSQTE
220
SMLINGYALN
230
CVVGSQGMPK
240
RIVNAKIACL
250
DFSLQKTKMK
260
LGVQVVITDP
270
EKLDQIRQRE
280
SDITKERIQK
290
ILATGANVIL
300
TTGGIDDMCL
310
KYFVETGAMA
320
VRRVLKRDLK
330
RIAKASGATI
340
LSTLANLEGE
350
ETFEASMLGQ
360
AEEVVQERIC
370
DDELILIKNT
380
KARTSASIIL
390
RGANDFMCDE
400
MERSLHDALC
410
VVRRVLESKS
420
VVPGGGAVEA
430
ALSIYLENYA
440
TSMGSREQLA
450
IAEFARSLLV
460
IPNTLAVNAA
470
QDSTDLVAKL
480
RAFHNEAQVN
490
PERKNLKWIG
500
LDLVNGKPRD
510
NKQAGVFEPT
520
IVKVKSLKFA
530
TEAAITILRI
540
DDLIKLHPES
550
KDDKHGGYED
AVHSGALDD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0140662 | ATP-dependent protein folding chaperone |
| Cellular Component | GO:0001669 | acrosomal vesicle |
| Cellular Component | GO:0044297 | cell body |
| Cellular Component | GO:0005832 | chaperonin-containing T-complex |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0000792 | heterochromatin |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0000242 | pericentriolar material |
| Cellular Component | GO:0002199 | zona pellucida receptor complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:1904874 | positive regulation of telomerase RNA localization to Cajal body |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0050821 | protein stabilization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.