Overview
| Uniprot ID | A0A8D1FF06 |
|---|
| Protein Name | Coatomer subunit zeta |
|---|
| Gene Name | COPZ1 |
|---|
| Organism | Sus scrofa |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 29 |
DGDRLFAKYYDDTYP |
| 39 |
DDTYPSVKEQKAFEK |
Function
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex
Protein Sequence
10
MEALILEPSL
20
YTVKAILILD
30
NDGDRLFAKY
40
YDDTYPSVKE
50
QKAFEKNIFN
60
KTHRTDSEIA
70
LLEGLTVVYK
80
SSIDLYFYVI
90
GSSYENELML
100
MAVLNCLFDS
110
LSQMLRKNVE
120
KRALLENMEG
130
LFLAVDEIVD
140
GGVILESDPQ
150
QVVHRVALRV
160
LQSAKEQIKW
SLLR
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0030126 |
COPI vesicle coat |
| Cellular Component |
GO:0000139 |
Golgi membrane |
| Biological Process |
GO:0006886 |
intracellular protein transport |
| Biological Process |
GO:0006890 |
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.