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Overview

Uniprot IDA0A8D1GRX2
Protein NameMitochondrial import inner membrane translocase subunit
Gene NameTIMM9
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
94 CSEHCLQKYLKMTQR

Function

Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space

Protein Sequence

10 DSTGSATPQP 20 RSGVVCESLC 30 SSKKSGLTGK 40 NTEAKVRQLL 50 FQNRKETHAS 60 EKFKEFLGTY 70 NKLTETCFLD 80 CVKDFTTREV 90 KPEENTCSEH 100 CLQKYLKMTQ 110 RISMRFQEYH 120 IQQNEALAAK AGLLGQPR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0042719 mitochondrial intermembrane space chaperone complex
Molecular Function GO:0046872 metal ion binding
Biological Process GO:0045039 protein insertion into mitochondrial inner membrane
Biological Process GO:0015031 protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.