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Overview

Uniprot IDA0A8D1K601
Protein NameJunctional adhesion molecule C
Gene NameJAM3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
88 GRAELLGKTSLKIWN

Function

Promotes chemotaxis of vascular endothelial cells and stimulates angiogenesis

Protein Sequence

10 MSKIVSSLIL 20 LFFFPSGCLT 30 GAVNLKSSNR 40 NPVVQEFESV 50 ELSCIITDSQ 60 TNDPRIEWKK 70 IQDEQTSYVF 80 FDNKIQGDLT 90 GRAELLGKTS 100 LKIWNVTRTD 110 SALYRCEVVA 120 RNDRKEIDEI 130 VIELTVQVKP 140 VPPACRVPRA 150 VPVGKAATLS 160 CQEGEGYPRP 170 HYSWYRNDVP 180 LPTDSRANPR 190 FRNSSFLLNP 200 ETGTLVFNAV 210 HKEDSGQYYC 220 IASNDAGSAR 230 CEEQDMEVYD 240 LNISGIIGGV 250 LVVLTVLALI 260 TAGICCAYRR 270 GYFINNKQNG 280 ESYKNPGKPD 290 GVNYIRTDEE 300 VRSRVRSDLT KDT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005923 bicellular tight junction
Cellular Component GO:0030057 desmosome
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0046982 protein heterodimerization activity
Molecular Function GO:0042803 protein homodimerization activity
Biological Process GO:0007155 cell adhesion
Biological Process GO:0030154 cell differentiation
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0048731 system development

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.