Search Results
Overview
| Uniprot ID | A0A8D1MRP3 |
|---|---|
| Protein Name | Septin |
| Gene Name | SEPTIN7 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 171 | FMKRLHEKVNIIPLI |
| 193 | PEECQQFKKQIMKEI |
| 198 | QFKKQIMKEIQEHKI |
| 204 | MKEIQEHKIKIYEFP |
| 358 | KEKVQKLKDSEAELQ |
| 74 | GPSHRIKKTVQVEQS |
| 82 | TVQVEQSKVLIKEGG |
Function
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation
Protein Sequence
10
MEIYGRSQQK
20
NLEGYVGFAN
30
LPNQVYRKSV
40
KRGFEFTLMV
50
VGESGLGKST
60
LINSLFLTDL
70
YSPEYPGPSH
80
RIKKTVQVEQ
90
SKVLIKEGGV
100
QLLLTIVDTP
110
GFGDAVDNSN
120
CWQPVIDYID
130
SKFEDYLNAE
140
SRVNRRQMPD
150
NRVQCCLYFI
160
APSGHGLKPL
170
DIEFMKRLHE
180
KVNIIPLIAK
190
ADTLTPEECQ
200
QFKKQIMKEI
210
QEHKIKIYEF
220
PETDDEEENK
230
LVKKIKDRLP
240
LAVVGSNTII
250
EVNGKRVRGR
260
QYPWGVAEVE
270
NGEHCDFTIL
280
RNMLIRTHMQ
290
DLKDVTNNVH
300
YENYRSRKLA
310
AVTYNGVDNN
320
KNKGQLTKSP
330
LAQMEEERRE
340
HVAKMKKMEM
350
EMEQVFEMKV
360
KEKVQKLKDS
370
EAELQRRHEQ
380
MKKNLEAQHK
390
ELEEKRRQFE
400
DEKANWEAQQ
410
RILEQQNSSR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0032154 | cleavage furrow |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0031105 | septin complex |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0005525 | GTP binding |
| Biological Process | GO:0051301 | cell division |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.