Search Results
Overview
| Uniprot ID | A0A8D1MWP9 |
|---|---|
| Protein Name | Septin |
| Gene Name | SEPTIN7 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 172 | FMKRLHEKVNIIPLI |
| 194 | PEECQQFKKQIMKEI |
| 199 | QFKKQIMKEIQEHKI |
| 205 | MKEIQEHKIKIYEFP |
| 359 | KEKVQKLKDSEAELQ |
| 75 | GPSHRIKKTVQVEQS |
| 83 | TVQVEQSKVLIKEGG |
Function
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation
Protein Sequence
10
MPAYAKSTQQ
20
KNLEGYVGFA
30
NLPNQVYRKS
40
VKRGFEFTLM
50
VVGESGLGKS
60
TLINSLFLTD
70
LYSPEYPGPS
80
HRIKKTVQVE
90
QSKVLIKEGG
100
VQLLLTIVDT
110
PGFGDAVDNS
120
NCWQPVIDYI
130
DSKFEDYLNA
140
ESRVNRRQMP
150
DNRVQCCLYF
160
IAPSGHGLKP
170
LDIEFMKRLH
180
EKVNIIPLIA
190
KADTLTPEEC
200
QQFKKQIMKE
210
IQEHKIKIYE
220
FPETDDEEEN
230
KLVKKIKDRL
240
PLAVVGSNTI
250
IEVNGKRVRG
260
RQYPWGVAEV
270
ENGEHCDFTI
280
LRNMLIRTHM
290
QDLKDVTNNV
300
HYENYRSRKL
310
AAVTYNGVDN
320
NKNKGQLTKS
330
PLAQMEEERR
340
EHVAKMKKME
350
MEMEQVFEMK
360
VKEKVQKLKD
370
SEAELQRRHE
380
QMKKNLEAQH
390
KELEEKRRQF
400
EDEKANWEAQ
410
QRILEQQNSS
R
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0032154 | cleavage furrow |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0031105 | septin complex |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0005525 | GTP binding |
| Biological Process | GO:0051301 | cell division |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.