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Overview

Uniprot IDA0A8D1S998
Protein NameLarge ribosomal subunit protein uL4
Gene NameRPL4
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
142 RRVNTTQKRYAICSA
187 VESYKKTKEAVLLLK
194 KEAVLLLKKLKAWND
197 VLLLKKLKAWNDIKK
203 LKAWNDIKKVYASQR
204 KAWNDIKKVYASQRM
261 VSKLNILKLAPGGHV
281 WTESAFRKLDELYGT
316 TDLSRILKSPEIQRA
36 LISVYSEKGESSGKN
381 DKAAAALKAKSGEKG
387 LKAKSGEKGVPDKKP
42 EKGESSGKNVTLPAV
433 TKKPAAEKKPAEKKP
438 AEKKPAEKKPTTEEK

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MLLLTCEKSA 20 SVACQYKYFP 30 FSQACARPLI 40 SVYSEKGESS 50 GKNVTLPAVF 60 KAPIRPDIVN 70 FVHTNLRKNN 80 RQPYAVSELA 90 GHQTSAESWG 100 TGRAVARIPR 110 VRGGGTHRSG 120 QGAFGNMCRG 130 GRMFAPTKTW 140 RRWHRRVNTT 150 QKRYAICSAL 160 AASALPALVM 170 SKGHRIEEVP 180 ELPLVVEDKV 190 ESYKKTKEAV 200 LLLKKLKAWN 210 DIKKVYASQR 220 MRAGKGKMRN 230 RRRIQRRGPC 240 IIYNEDNGII 250 KAFRNIPGIT 260 LLNVSKLNIL 270 KLAPGGHVGR 280 FCIWTESAFR 290 KLDELYGTWR 300 KAATLKSNYN 310 LPMHKMLNTD 320 LSRILKSPEI 330 QRALRAPRKK 340 IHRRVLKKNP 350 LKNLRIMLKL 360 NPYAKTMRRN 370 TILRQARNHK 380 IRMDKAAAAL 390 KAKSGEKGVP 400 DKKPVVEKKG 410 KKAIGKKAVG 420 VKKQKKPLVG 430 KKAVVTKKPA 440 AEKKPAEKKP TTEEKKAVA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005791 rough endoplasmic reticulum
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0002181 cytoplasmic translation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.