Search Results

Overview

Uniprot IDA0A8D1SVA6
Protein NameUDP-glucose ceramide glucosyltransferase-like 1
Gene NameUGGT1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1361 QIVRTDLKELRDFSL
1495 NPMTKEPKLEAAVRI
222 TSKSNAGKINYIFRH
362 TKARAITKTAVSSEL
957 PKGDTRIKYQFFEDR

Function

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation

Protein Sequence

10 MGWKGAAGGA 20 CAAAARPVTG 30 VCHKMGLLII 40 LIGLWLLSSV 50 KADSKAITTS 60 LTTKWFSTPL 70 LLEASEFLAE 80 DSQEKFWNFV 90 EASQNIGSSD 100 HHGTDYAYYH 110 AILEAAFQFL 120 SPLQQNLLKF 130 CLSLRSYSAT 140 IQAFQQIAAD 150 EPPPEGCNSF 160 FSVHGKRSCD 170 FDTLETLLLT 180 ASERPKPLLF 190 KGDHRYPSSN 200 PESSVVIFYS 210 EIGSEEFYNF 220 HRQLTSKSNA 230 GKINYIFRHY 240 IPNPRKEPVY 250 LSGYGVELAI 260 KSTEYKAKDD 270 TQVKGTEVNT 280 TVIGENDPID 290 EVQGFLFGKL 300 RDLHPDLKGQ 310 LKELRKHLVE 320 STNEMAPLKV 330 WQLQDLSFQT 340 AARILAAPIE 350 LALVIMKDLS 360 QNFPTKARAI 370 TKTAVSSELR 380 TEVEENQKYF 390 KGALGLQPGD 400 SALFINGLHI 410 DLETQDIFSL 420 FDILRNEARV 430 MEGLHRLGIE 440 GLSLHNILKL 450 NIQPSEADYA 460 VDIRSPAISW 470 INNLELDSRY 480 SSWPSSLQEL 490 LRPTFPGVIR 500 QIRKNLHNMV 510 FIVDPAHEST 520 AELINTAEMF 530 LSNHIPLRLG 540 LIFVVNDSED 550 VDGMQDAGVA 560 LLRAYNYVAQ 570 EMDDYHAFQT 580 LTHIYNKVRT 590 GEKVKVEHVV 600 SVLEKKYPYV 610 EVNSILGIDS 620 AYDQNRKEAR 630 GYYEQTGVGP 640 LPVVLFNGMP 650 LEKEQLDPDE 660 LETITMHKIL 670 ETTTFFQRAV 680 YLGELSLDQD 690 VVEYIMNQPN 700 VVPRINSRIL 710 TAEREYLDLT 720 ATNNFFVDDY 730 ARFTVLDSQG 740 KTTAIANSMN 750 YLTKKDDSFI 760 RPVTFWIVGD 770 FDSPSGRQLL 780 YDAIKHQKSS 790 NNVRIGMINN 800 PSEDISYEKT 810 QISRAIWAAL 820 QTQTSNSAKN 830 FITKMAKEET 840 AEALAAGADI 850 SEFSVGGMDF 860 SLFKEVFESS 870 KMDFILSHAM 880 YCRDVLKLKK 890 GQRAVISNGR 900 IIGPLEDSEL 910 FNQDDFHLLE 920 NIILKTSGQK 930 IKSHIQQLRV 940 EEDVASDLVM 950 KVDALLSAQP 960 KGDTRIKYQF 970 FEDRHSAIKL 980 KPKEGETYFD 990 VVAVVDPVTR 1000 EAQRLAPLLL 1010 VLTQLINMNL 1020 RVFMNCQSKL 1030 SDMPLKSFYR 1040 YVLEPEISFS 1050 SDNSFAKGPI 1060 AKFLDMPQSP 1070 LFTLNLNTPE 1080 SWMVESVRTP 1090 YDLDNIYLEE 1100 VDSIVAAEYE 1110 LEYLLLEGHC 1120 YDITTGQPPR 1130 GLQFTLGTSA 1140 KPVIVDTIVM 1150 ANLGYFQLKA 1160 NPGAWILRLR 1170 KGRSEDIYRI 1180 YSHDGTDSPP 1190 DADEVVVVLN 1200 NFKSKIIKVK 1210 VQKKADMVNE 1220 DLLSDGTNEN 1230 ESGFWDSFKW 1240 GFTGGQKTEE 1250 VKQDKDDVIN 1260 IFSVASGHLY 1270 ERFLRIMMLS 1280 VLKNTKTPVK 1290 FWFLKNYLSP 1300 TFKEFIPYMA 1310 NKYNFQYELV 1320 QYKWPRWLHQ 1330 QTEKQRIIWG 1340 YKILFLDVLF 1350 PLVVDKFLFV 1360 DADQIVRTDL 1370 KELRDFSLDG 1380 APYGYTPFCD 1390 SRREMDGYRF 1400 WKSGYWASHL 1410 AGRKYHISAL 1420 YVVDLKKFRK 1430 IAAGDRLRGQ 1440 YQGLSQDPNS 1450 LSNLDQDLPN 1460 NMIHQVPIKS 1470 LPQEWLWCET 1480 WCDDASKKRA 1490 KTIDLCNNPM 1500 TKEPKLEAAV 1510 RIVPEWQDYD 1520 QEIKQLQTRF 1530 QEEKEMGTLY 1540 KDMTAEEPSR EGPQKREEL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005788 endoplasmic reticulum lumen
Molecular Function GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process GO:0009101 glycoprotein biosynthetic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.