Search Results
Overview
| Uniprot ID | A0A8D1T8W8 |
|---|---|
| Protein Name | Hsp90 co-chaperone Cdc37 |
| Gene Name | CDC37 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 112 | EVREQKHKTFVEKYE |
| 117 | KHKTFVEKYEKQIKH |
| 190 | LELAKSLKVDPRACF |
| 30 | AECQRKLKELEVAEG |
| 56 | AEAQQLLKEERSWEQ |
| 6 | **MEQFQKEKEELDR |
| 8 | MEQFQKEKEELDRGC |
Function
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity
Protein Sequence
10
MEQFQKEKEE
20
LDRGCRECKR
30
KVAECQRKLK
40
ELEVAEGEGG
50
EAELERLQAE
60
AQQLLKEERS
70
WEQKLEEMRK
80
KEKSMPWNVD
90
TLSKDGFSKS
100
MVNTKPEQAE
110
EESEEVREQK
120
HKTFVEKYEK
130
QIKHFGMLRR
140
WDDSQKYLSD
150
NVHLVCEETA
160
NYLVIWCIDL
170
EVEEKCALME
180
QVAHQTIVMQ
190
FILELAKSLK
200
VDPRACFRQF
210
FTKIKTADRQ
220
YMEGFNDELE
230
AFKDRVRGRA
240
KLRIEKAMKE
250
YEEEERKKRL
260
GPGGLDPVEV
270
YESLPEELQK
280
CFDAKDVQML
290
QDAISKMDPT
300
DAKYHMQRCI
310
DSGLWVPNSK
320
SSEAKEGEEA
330
GPGDPLLEAA
340
SKSGDEKDVS
A
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0031072 | heat shock protein binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0050821 | protein stabilization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.