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Overview

Uniprot IDA0A8D1TCI3
Protein NameThioredoxin-related transmembrane protein 2
Gene NameTMX2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
169 TDVSTRYKVSTSPLT

Function

Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain

Protein Sequence

10 MAVLAPLIAL 20 IYSIPRLSRW 30 LARPYYLLSA 40 LLSAAFLLVR 50 KLPPVCYNLP 60 TQREDGNPCD 70 FDWREVEILM 80 FLSAIVMMKN 90 RRSMFLMTCK 100 PPLYMGPEYI 110 KYFSDKTIDE 120 ELARDKRVTW 130 IVEFFANWSN 140 DCQSFAPIYA 150 DLSLKYNCTG 160 LNFGKVDVGR 170 YTDVSTRYKV 180 STSPLTKQLP 190 TLILFQGGKE 200 VMRRPQIDKK 210 GRAVSWTFSE 220 ENVIREFNLN 230 ELYHRAKKVS 240 KAGDNIPEEE 250 PIAQTPTAAP DQESKKDK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0031966 mitochondrial membrane

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.