Search Results

Overview

Uniprot IDA0A8D1UC68
Protein NameUDP-glucose ceramide glucosyltransferase-like 1
Gene NameUGGT1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1369 QIVRTDLKELRDFSL
1503 NPMTKEPKLEAAVRI
222 TSKSNAGKINYIFRH
362 TKARAITKTAVSSEL
965 PKGDTRIKYQFFEDR

Function

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation

Protein Sequence

10 MGWKGAAGGA 20 CAAAARPVTG 30 VCHKMGLLII 40 LIGLWLLSSV 50 KADSKAITTS 60 LTTKWFSTPL 70 LLEASEFLAE 80 DSQEKFWNFV 90 EASQNIGSSD 100 HHGTDYAYYH 110 AILEAAFQFL 120 SPLQQNLLKF 130 CLSLRSYSAT 140 IQAFQQIAAD 150 EPPPEGCNSF 160 FSVHGKRSCD 170 FDTLETLLLT 180 ASERPKPLLF 190 KGDHRYPSSN 200 PESSVVIFYS 210 EIGSEEFYNF 220 HRQLTSKSNA 230 GKINYIFRHY 240 IPNPRKEPVY 250 LSGYGVELAI 260 KSTEYKAKDD 270 TQVKGTEVNT 280 TVIGENDPID 290 EVQGFLFGKL 300 RDLHPDLKGQ 310 LKELRKHLVE 320 STNEMAPLKV 330 WQLQDLSFQT 340 AARILAAPIE 350 LALVIMKDLS 360 QNFPTKARAI 370 TKTAVSSELR 380 TEVEENQKYF 390 KGALGLQPGD 400 SALFINGLHI 410 DLETQDIFSL 420 FDILRNEARV 430 MEGLHRLGIE 440 GLSLHNILKL 450 NIQPSEADYA 460 VDIRSPAISW 470 INNLELDSRY 480 SSWPSSLQEL 490 LRPTFPGVIR 500 QIRKNLHNMV 510 FIVDPAHEST 520 AELINTAEMF 530 LSNHIPLRLG 540 LIFVVNDSED 550 VDGMQDAGVA 560 LLRAYNYVAQ 570 EMDDYHAFQT 580 LTHIYNKVRT 590 GEKVKVEHVV 600 SVLEKKYPYV 610 EVNSILGIDS 620 AYDQNRKEAR 630 GYYEQTGVGP 640 LPVVLFNGMP 650 LEKEQLDPDE 660 LETITMHKIL 670 ETTTFFQRAV 680 YLGELSLDQD 690 VVEYIMNQPN 700 VVPRINSRIL 710 TAEREYLDLT 720 ATNNFFVDDY 730 ARFTVLDSQG 740 KTTAIANSMN 750 YLTKKGMSSK 760 EIYDDSFIRP 770 VTFWIVGDFD 780 SPSGRQLLYD 790 AIKHQKSSNN 800 VRIGMINNPS 810 EDISYEKTQI 820 SRAIWAALQT 830 QTSNSAKNFI 840 TKMAKEETAE 850 ALAAGADISE 860 FSVGGMDFSL 870 FKEVFESSKM 880 DFILSHAMYC 890 RDVLKLKKGQ 900 RAVISNGRII 910 GPLEDSELFN 920 QDDFHLLENI 930 ILKTSGQKIK 940 SHIQQLRVEE 950 DVASDLVMKV 960 DALLSAQPKG 970 DTRIKYQFFE 980 DRHSAIKLKP 990 KEGETYFDVV 1000 AVVDPVTREA 1010 QRLAPLLLVL 1020 TQLINMNLRV 1030 FMNCQSKLSD 1040 MPLKSFYRYV 1050 LEPEISFSSD 1060 NSFAKGPIAK 1070 FLDMPQSPLF 1080 TLNLNTPESW 1090 MVESVRTPYD 1100 LDNIYLEEVD 1110 SIVAAEYELE 1120 YLLLEGHCYD 1130 ITTGQPPRGL 1140 QFTLGTSAKP 1150 VIVDTIVMAN 1160 LGYFQLKANP 1170 GAWILRLRKG 1180 RSEDIYRIYS 1190 HDGTDSPPDA 1200 DEVVVVLNNF 1210 KSKIIKVKVQ 1220 KKADMVNEDL 1230 LSDGTNENES 1240 GFWDSFKWGF 1250 TGGQKTEEVK 1260 QDKDDVINIF 1270 SVASGHLYER 1280 FLRIMMLSVL 1290 KNTKTPVKFW 1300 FLKNYLSPTF 1310 KEFIPYMANK 1320 YNFQYELVQY 1330 KWPRWLHQQT 1340 EKQRIIWGYK 1350 ILFLDVLFPL 1360 VVDKFLFVDA 1370 DQIVRTDLKE 1380 LRDFSLDGAP 1390 YGYTPFCDSR 1400 REMDGYRFWK 1410 SGYWASHLAG 1420 RKYHISALYV 1430 VDLKKFRKIA 1440 AGDRLRGQYQ 1450 GLSQDPNSLS 1460 NLDQDLPNNM 1470 IHQVPIKSLP 1480 QEWLWCETWC 1490 DDASKKRAKT 1500 IDLCNNPMTK 1510 EPKLEAAVRI 1520 VPEWQDYDQE 1530 IKQLQTRFQE 1540 EKEMGTLYKD 1550 MTAEEPSREG PQKREEL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005788 endoplasmic reticulum lumen
Molecular Function GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process GO:0009101 glycoprotein biosynthetic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.